Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Healthcare professionals' perceptions of participation in one state physician health program. [PDF]
Am J AddictAraujo CNP +6 more
europepmc +1 more source
A Practical guide to public health laboratories for state health officials [PDF]
"Representatives from the Association of State and Territorial Health Of!cials (ASTHO) and the Association of Public Health Laboratories (APHL) saw future issues looming -- primarily funding issues, but also IT, biosecurity, and emerging health threats -
Association of Public Health Laboratories (U.S.)
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
State of Health Estimation for Lithium-Ion Batteries via Fused Impedance Feature and V‑Transformer-AGLU Network. [PDF]
ACS OmegaFang Y +6 more
europepmc +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Multiphysics Measurement Method for Supercapacitors State of Health Determination. [PDF]
Micromachines (Basel)Doucet T +6 more
europepmc +1 more source
Healthy Connecticut. 2. State health improvement plan. 2020.
, 2014 Consultant: Health Resources in Action, Boston, Massachusetts.; Includes bibliographical references.; Funded by the Centers for Disease Control and Prevention, Office for State, Tribal, Local and Territorial SupportPart 1.
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