Results 151 to 160 of about 4,327,149 (349)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Biennial report of the State Board of Health of Maryland.
, 1876 Printers vary.First issue (1876) covers period May 6, 1874-Dec.
Maryland. State Board of Health.
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FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Biennial report of the Minnesota State Board of Health and Vital Statistics of Minnesota.
, 1923 Mode of access ...
Minnesota. State Board of Health.
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
, 1981 Title from PDF cover (viewed on August 8, 2019).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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, 2016 The Office of State Auditor audited the financial statements of the South Carolina Department of Mental Health using agreed upon procedures. The following topics were included in the audit: cash receipts/revenues, cash disbursements/non-payroll ...
South Carolina Office of the State Auditor +1 more
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
, 1934 1934 Bulletin of the Kansas State Board of Health. Publication of the monthly/quarterly Bulletin of the Kansas State Board of Health ceased with the April-June 1924 issue. After that date the Bulletin consisted of monographic "Special Numbers"
Kansas State Board of Health. Division of Sanitation.
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source