Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Effects of Ownership and Financial Status on Corporate Environmental Performance [PDF]
This paper analyzes the effects of ownership structure on corporate environmental performance and examines the link between financial performance to environmental performance in a transition economy. In particular, it analyzes these ownership effects and
Dietrich Earnhart, Lubomir Lizal
core
Firm Performance and the Political Economy of Corporate Governance: Survey Evidence for Bulgaria, Hungary, Slovakia and Slovenia [PDF]
, 2000 Using survey data for 220 traditional manufacturing firms over 7 years of transition and 4 CEE countries, we find firms that produced for the EU market under planning consistently outperform those that produced for the CMEA market.
Walsh, Patrick Paul, Whelan, Ciara
core
How Important is Ownership in a Market with Level Playing Field? The Indian Banking Sector Revisited [PDF]
, 2002 It has long been argued that private ownership of firms leads to better firm performance. However, theory as well as empirical evidence suggest that factors like agency problems may not allow privately owned firms to operate more efficiently or perform ...
Bhaumik, Sumon Kumar, Dimova, Ralitza
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Federal state shareholdings in Russian companies: Origin, forms and consequences for enterprise perfomance [PDF]
This paper studies the impact of federal state shareholdings on the performance of Russian companies. It differs from most similar studies in two respects.
Alexander Muravyev
core +3 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
State Ownership and Labor Cost Stickiness: The Role of Free Cash Flows [PDF]
پژوهشهای تجربی حسابداریThe purpose of this study is to examine the effect of free cash flows on the relationship between government ownership and labor cost stickiness while providing evidence of how non-economic considerations and socio-political goals influence cost behavior.
Azam Pouryousof +2 more
doaj +1 more source
Acquisitions in the Electricity Sector: Active vs. Passive Owners [PDF]
The starting point of this paper is a mixed oligopoly market consisting of n privately owned profit maximizing firms and 1 state-owned welfare maximizing firm. Motivated by the trend of mergers and acquisitions in the liberalized electricity markets, and
Nese, Gjermund
core