Results 81 to 90 of about 94,485 (267)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Options for the restructuring of state ownership of South African Airways
Journal of Transport and Supply Chain Management, 2018 Background: South Africa adopted an economic policy that included both deregulation and privatisation in line with the 1980s’ global trends. Economic deregulation of the domestic air transport market was implemented in 1991 and partial privatisation of ...
Joachim Vermooten
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Agricultural Economics (AGRICECON), 2003 In Hungary, after the political and economical transition period of the nineties, the transformation of agriculture, the privatisation and the partial compensation brought about fundamental change in the land ownership structure.
J. Popp, M. Stauder
doaj +1 more source
International evidence on state ownership and trade credit: Opportunities and motivations. [PDF]
J Int Bus Stud, 2021 Chen R +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Leadership, religiousness, state ownership of an enterprise and unethical pro-organizational behavior: The mediating role of organizational identification. [PDF]
PLoS One, 2021 Gigol T.
europepmc +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Sage OpenThe sustainability of private enterprises is foundational to the high-quality development of the national economy. This paper investigates the role of state ownership in enhancing the sustainable development of private enterprises, utilizing data of A-share private enterprises in China from 2009 to 2022.
Fengzuo Li +4 more
openaire +2 more sources