Results 31 to 40 of about 15,184 (193)

The development of the monographs for compoundED preparations for the state pharmacopoeia of Ukraine

Регуляторные исследования и экспертиза лекарственных средств, 2018
At present, there are certain topical issues related to the development of the standards for preparation and quality control of compounded medicines, the elaboration of quality assurance system for compounded preparations under the state policy ...
A. A. Zdoryk, L. P. Savchenko, V. A. Georgiyants, A. I. Gryzodub   +3 more
doaj  

GAP analysis and SWOT analysis of pharmacopoeial quality standards of Calendulae flos: experience of Ukraine and France

Annals of Mechnikov's Institute
The article considers the issue of harmonization of requirements for standardization of medicinal plant raw materials using the example of Calendula officinalis flowers in the context of the State Pharmacopoeia of Ukraine and the Pharmacopée française ...
Viktoriia Shapovalova, Olena Lavoshnyk, Valentyn Shapovalov, Alina Osyntseva, Valerii Shapovalov   +4 more
doaj   +1 more source

Ashwagandha: Is It Safe? Part 1: A Regulatory Review

Phytotherapy Research, EarlyView.
ABSTRACT Over the last decade, ashwagandha (Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler, R. Al‐Mondhiry, L. Lang, R. Marles, M. Tallon, A. Raghu   +5 more
wiley   +1 more source

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

Phytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou, Jingyun Chi, Yuan Ding, Zhidi Zhang, Rui Liang, Tianhao Wang, Yan Jiang, Rujun Song, Huazhou Fu, Xizhen Zhou   +9 more
wiley   +1 more source

General monographs and pharmacopoeial monographs of the State pharmacopoeia of Russian Federation XIII edition

Регуляторные исследования и экспертиза лекарственных средств, 2018
The State Pharmacopoeia of the Russian Federation is a collection of general monographs and pharmacopoeial monographs. It should be reissued at least once in 5 years.
V. A. Merkulov, E. I. Sakanyan, T. B. Shemeryankina, O. A. Mochikina, N. D. Bunyatyan   +4 more
doaj  

Pseudorandomised controlled trial of a novel navel barrier solution versus 10% iodine to protect navel and ear tag sites of neonatal lambs

Veterinary Record, EarlyView.
Abstract Background During lambing, 10% iodine is often used to protect neonatal navel and ear tag sites. The evidence for its effectiveness is sparse. Recently, a specific navel barrier solution (NBS) was developed. Here, an in vivo field trial compared the two treatments. Methods Ten farms reported data from 6840 lambs. The navel and ear tag sites of
Fiona M. Lovatt, Jonathan J. Powell, Carlos A. P. Bastos, Ian S. McCrone   +3 more
wiley   +1 more source

Five‐Grass‐Pollen Sublingual Immunotherapy Drops Are Efficacious and Well Tolerated in Adults: The RHAPSODY Phase III Trial

Allergy, EarlyView.
The RHAPSODY multinational study investigated 26 months of continuous treatment with 5‐grass‐pollen sublingual SLIT drops in adults with moderate‐to‐severe grass‐pollen‐induced allergic rhinoconjunctivitis. The primary efficacy endpoint (the average daily total combined score) showed statistically significant differences in favour of the active ...
Alain Didier, Ruta Gronskyte Juhl, Terrie Dalgaard, Antoine Chartier, Philippe Devillier   +4 more
wiley   +1 more source

Equivalence assessment of quantitative tannins determination methods, used for analysis of herbal drugs

Регуляторные исследования и экспертиза лекарственных средств, 2018
The article describes results of comparative evaluation of two pharmacopoeial methods used for quantitative determination of tannins in herbal drugs: the titrimetric method of the State Pharmacopoeia of the USSR (XIth edition) that is described in the ...
N. P. Antonova, A. M. Kalinin, S. S. Prohvatilova, E. P. Shefer, T. E. Matveenkova   +4 more
doaj  

Quality standard of traditional Chinese medicines: comparison between European Pharmacopoeia and Chinese Pharmacopoeia and recent advances

Chinese Medicine, 2020
Traditional Chinese medicine (TCM) are becoming more and more popular all over the world. However, quality issues of TCM may lead to medical incidents in practice and therefore quality control is essential to TCM.
Fong Leong, Xue Hua, Mei Wang, Tongkai Chen, Yuelin Song, Pengfei Tu, Xiao-Jia Chen   +6 more
doaj   +1 more source

Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

Alimentary Pharmacology &Therapeutics, EarlyView.
We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo, Sepideh Mehravar, Ellen Choi, Ju Dong Yang, Hyun‐Seok Kim, Yun Wang, Aarshi Vipani, Hirsh D. Trivedi, Walid Ayoub, Parnian Naji, Alexander Kuo, Chun‐Ying Wu, Lorenzo Leggio, Juan Pablo Arab   +13 more
wiley   +1 more source