Results 61 to 70 of about 7,645,590 (291)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Hierarchical Framework of Cloud Resource Allocation and Power Management Using Deep Reinforcement Learning

, 2017
Automatic decision-making approaches, such as reinforcement learning (RL), have been applied to (partially) solve the resource allocation problem adaptively in the cloud computing system.
Li, Zhe, Lin, Sheng, Liu, Ning, Qiu, Qinru, Tang, Jian, Wang, Yanzhi, Xu, Jielong, Xu, Zhiyuan   +7 more
core   +1 more source

Principles of independence and accountability in the activities of the European Central Bank and the central bank of the EU member state

Аналітично-порівняльне правознавство
The scientific article is devoted to the study of the principles of independence and accountability in the activities of the European Central Bank and the central bank of the EU member state. The article focuses attention on Art. 108 and Art.
R.P. Naturkach
doaj   +1 more source

POWER POLICY IN THE EUROPEAN UNION. NEW DIMENSIONS OF SECURITY [PDF]

Annals: Series on Military Sciences, 2020
A review about the european power policy. Fundaments, definitions and historical backgrounds, contemporary and future prospects. Understanding the european power policy under it`s all aspects of economic, culture, political and military impact.
Cristian-Petru VINTILĂ, Phd. candidate
doaj  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Discovery of multiple Lorentzian components in the X-ray timing properties of the Narrow Line Seyfert 1 Ark 564

, 2007
We present a power spectral analysis of a 100 ksec XMM-Newton observation of the narrow line Seyfert 1 galaxy Ark~564. When combined with earlier RXTE and ASCA observations, these data produce a power spectrum covering seven decades of frequency which is
Arévalo, Arévalo, Axelsson, Axelsson, Belloni, Blandford, Botte, Brinkmann, Christopoulou, D. P. Summons, Edelson, Fabian, Gierliński, I. E. Papadakis, I. M. McHardy, Kotov, Lal, Lyubarskii, M. J. Page, Markowitz, McHardy, McHardy, McHardy, Miller-Jones, Nowak, Nowak, P. Arévalo, P. Uttley, Papadakis, Papadakis, Papadakis, Papadakis, Peterson, Pottschmidt, Pounds, Remillard, Revnivtsev, Romano, Schmitt, Summons, Turner, Uttley, Uttley, W. Brinkmann   +43 more
core   +1 more source

New Directions and Channels of State-Civil Interaction in Russia During the Special Military Operation

Управленческое консультирование
This article examines the problem of transformation of the state-civil dialogue in conditions of political instability. The purpose of the study is to analyze the process of development of civil society in the Russian Federation in the period after the ...
D. L. Tsybakov, A. A. Salomatina
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Local Protection: Raising a Matter of \u27Sovereign Concern\u27 [PDF]

, 2001
Challenges to the expansion of local initiatives aimed at local environmental protection question the powers delegated to municipal governments from the state.
Nolon, John R.
core   +1 more source