Results 71 to 80 of about 25,475,738 (290)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
International Journal of Communication, 2022 This article examines how states adopt visual activist strategies to promote and legitimize their own narratives in today’s digital environment. Specifically, it tackles the work of the Israel Defense Forces (IDF) Documentary-Combat squad, a new unit ...
Anat Leshnick
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Power Data- collection of reports; Preliminary power studies
, 1931 Series 1173 | State Planning Board | Power resources records | Power Data- collection of reports; Preliminary power studiesOne of the duties of the State Planning Board was to plan for the conservation and development of the natural resources of the ...
State Planning Board
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Public administration information power: the impact of global trends
Lex Portus, 2019 The comprehensive informatization of a society, the widespread introduction of new information technologies updated the discussions about the information power as a function of public administration in its broadest understanding. In modern conditions the
Antoshina Iryna
doaj +1 more source
Papers Concerning College Power Plant : Correspondence of President E. G. Peterson
, 1929 Correspondence of Utah State Agricultural College President, Elmer George Peterson, concerning the College Power Plant. Magor correspondents include: George D. Clyde (Dean of Engineering), and J. N.
Peterson, E. G. (Elmer George), 1882-1958;
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Power Data- collection of reports; Power distribution
, 1931 Series 1173 | State Planning Board | Power resources records | Power Data- collection of reports; Power distributionOne of the duties of the State Planning Board was to plan for the conservation and development of the natural resources of the state ...
State Planning Board
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source