Results 61 to 70 of about 1,413,084 (263)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Vaarao Amenhotep IV (Ehnatoni) riigivalitsemisviisi võimalikust eripärast [PDF]
The article explores the relationship between the religious reform of Pharaoh Amenhotep IV (Akhenaten) of the New Kingdom of Ancient Egypt and changes in the government system.
Tarmo Kulmar
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
This article examines how states adopt visual activist strategies to promote and legitimize their own narratives in today’s digital environment. Specifically, it tackles the work of the Israel Defense Forces (IDF) Documentary-Combat squad, a new unit ...
Anat Leshnick
doaj
State, power and global order [PDF]
This article examines the evolution of international thought through the notion of ‘political space’. It focuses on two important domains of international politics, the nation-state and the global, to reflect on spatial categories in the discipline of International Relations (IR).
openaire +2 more sources
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Siyasal Ekoloji Çerçevesinde Devlet Kudretinin Yeşilleşmesine İlişkin Bir Tartışma
Bu çalışma kapsamında siyasal ekolojinin ideolojik temellerinden hareketle modern devlet iktidarının (Levitahan’ın) yeşilleşmesi incelenmiştir. Bu doğrultuda ekolojizm çerçevesinde tartışılan küresel çevresel değişimler, biyoçeşitlilik, iklim krizi ...
A. Aslı Şimşek Öner
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
State of Exception and Judicial Power [PDF]
State of Exception and Judicial Power The article deals with the concept of the state of exception in judicial reasoning. Two cases from the European Court of Human Rights together with some case law of the Lithuanian Constitutional Court are examined.
openaire +2 more sources

