Results 161 to 170 of about 27,759,159 (289)

Score Distributions of the Mini-Mental State Examination, Clock Drawing Test, and Reisberg Global Deterioration Scale Across Operational Cognitive Impairment Severity Strata in Romanian Primary Care: A Cross-Sectional Descriptive Study. [PDF]

J Clin Med
Popa E, Haliga RE, Coșovanu EO, Barbacariu CL, Ungureanu MI, Poroch M, Barbu MR, Coman EA.   +7 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

York Ballot Audit Report - 2014 Primary Election

, 2014
This audit report by the South Carolina State Election Commission for the 2014 Primary Election in York County provides reports generated by the iVotronic voting machines and Unity election ...
South Carolina State Election Commission
core  

Response Characteristics of Key Filtering Parameters and Applicability of Interference Detection for Integrated Navigation Under Spoofing Interference. [PDF]

Sensors (Basel)
Zhao S, Fu J, Li B, Jiang P.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Measurement of Treatment Adequacy Influences Estimates of Racial Disparities in Endometrial Cancer Care. [PDF]

Cancer Epidemiol Biomarkers Prev
Felix AS, Meade CE, Kanal SA, Medina HN, Quick AM, Padamsee TJ, Sinnott JA.   +6 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

A Dual-Clock Stability Feature-Based Noise-Adaptive Clock Steering Approach for Single-Satellite Time Reference Generation. [PDF]

Sensors (Basel)
Xiang Y, Chen L, Liu Y, Jiang B, Li L.
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Systematic review for reliability and validity of ultrasound imaging for femoral cartilage morphology and composition against MRI: protocol. [PDF]

BMJ Open
Nagahori H, Goodman X, Teng HL, Ho KY.
europepmc   +1 more source