Results 51 to 60 of about 314,624 (198)

Relative sensor registration with two-step method for state estimation

Cognitive Computation and Systems, 2019
State estimation suffers from some new challenging problems with a multi-platform multi-sensor observation system. An important problem for multisensor integration is that the data from the local sensors needs to be transformed into a common reference ...
Quanbo Ge, Tianxiang Chen, Tianxiang Chen, Zhansheng Duan, Mingxin Liu, Zhuyun Niu   +5 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Trend analysis and age-period-cohort effects on morbidity and mortality of liver cancer from 2010 to 2020 in Guangzhou, China

Frontiers in Oncology
IntroductionLiver cancer is one of the most common malignant gastrointestinal tumors worldwide. This study intends to provide insight into the epidemiological characteristics and development trends of liver cancer incidence and mortality from 2010 to ...
Dedong Wang, Dedong Wang, Dedong Wang, Xiangzhi Hu, Huan Xu, Yuanyuan Chen, Suixiang Wang, Guozhen Lin, Lei Yang, Jinbin Chen, Lin Zhang, Pengzhe Qin, Di Wu, Di Wu, Di Wu, Boheng Liang   +15 more
doaj   +1 more source

Corrosion Behavior of N80 Steel in CO₂ Flooding Produced Water [PDF]

Cailiao Baohu
For investigate the corrosion behavior of N80 steel at different depths of wells during production， high-temperature and highpressure reactors were used to simulate the corrosion conditions of CO2 flooding wells.The corrosion products and ...
XIE Hui, YU Chao, HUA Jing, JIANG Xiu
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

The Problem of the Relation of Hate and Enmity Under Article 282 Through the Prism of Publicity and Media

Сибирское юридическое обозрение, 2011
The distinction and relation of concepts of «hatred» and of «hostility». The problematic issues of qualification incite hatred or enmity are considered.
Yuliy Evgenievna Puhir
doaj  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Archaeological Heritage Sites: State Cadastral Registration and State Protection

СибСкрипт
Archaeological heritage sites are a special object of real estate; they have a particular legal status and state protection issues. This article describes the state cadastral registration of archaeological monuments and sites, as well as the function of ...
Yu. Yu. Gizey
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source