In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Correction: Wu et al. 3D-Printed Multi-Stimulus-Responsive Hydrogels: Fabrication and Characterization. Micromachines 2025, 16, 788. [PDF]
Wu J, Ma Z, Tang Q, Yang R.
europepmc +1 more source
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Correction: Chen et al. Evolutionary Insights and Flowering Regulation of <i>SPLs</i> in Coconut Palm. <i>Plants</i> 2025, <i>14</i>, 2532. [PDF]
Chen R +11 more
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Correction: Yu, C.; Song, Y.S. Characterization of Phase Change Materials Fabricated with Cross-Linked Graphene Aerogels. Gels 2022, 8, 572. [PDF]
Yu C, Song YS.
europepmc +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
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Correction: Yang et al. Nutrient-Driven Metabolic Activation and Microbial Restructuring Induced by Endophytic <i>Bacillus</i> in Blight-Affected Forest Soils. <i>Microorganisms</i> 2025, <i>13</i>, 1454. [PDF]
Yang Q, Tan S, Niu A, Liu J, Zhou G.
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ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
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