Results 81 to 90 of about 1,023,856 (306)
Risks, 2017 This paper gives a detailed overview of the current state of research in relation to the use of state space models and the Kalman-filter in the field of stochastic claims reserving.
Nataliya Chukhrova, Arne Johannssen
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Bootstrap Approximation to Prediction MSE for State-Space Models with Estimated Parameters
, 2004 We propose a simple but general bootstrap method for estimating the Prediction Mean Square Error (PMSE) of the state vector predictors when the unknown model parameters are estimated from the observed series.
Pfeffermann, Danny, Tiller, Richard
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
State space c-reductions for concurrent systems in rewriting logic
, 2011 We present c-reductions, a state space reduction technique. The rough idea is to exploit some equivalence relation on states (possibly capturing system regularities) that preserves behavioral properties, and explore the induced quotient system.
Lluch-Lafuente, Alberto +8 more
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
IEEE Access, 2019 The autonomic nervous system (ANS) stimulates various sweat glands for maintaining body temperature as well as in response to various psychological events. Variations in skin conductance (SC) measurements due to salty sweat secretion can be used to infer
MD. Rafiul Amin, Rose T. Faghih
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Subspace system identification
Iranian Journal of Electrical and Electronic Engineering, 2005 We give a general overview of the state-of-the-art in subspace system identification methods. We have restricted ourselves to the most important ideas and developments since the methods appeared in the late eighties.
J. Poshtan, H. Mojallali
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