Results 61 to 70 of about 889,599 (262)

THE MODELLING OF A BUS SUSPENSION SYSTEM USING MATLAB/SIMULINK [PDF]

open access: yesFiabilitate şi Durabilitate, 2019
The purpose of vehicle suspension system is to improve ride comfort and road handling.1/4th model of bus suspension system is used to simplify the problem.
Gheorghe GÎLCĂ
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Linear Offset-Free Model Predictive Control in the Dynamic PLS Framework

open access: yesInformation, 2018
This work addresses the model predictive control (MPC) of the offset-free tracking problem in the dynamic partial least square (DyPLS) framework. Firstly, state space MPC based on the DyPLS is proposed.
Ligang Hou, Ze Wu, Xin Jin, Yue Wang
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

MCMC for State Space Models

open access: yes
This review article is intended for the second edition of The Handbook of MCMC and is a substantial revision of the chapter of the same name that appeared in the first edition.
Fearnhead, Paul, Sherlock, Chris
openaire   +2 more sources

Comparison of VSC and Z-Source Converter: Power System Application Approach

open access: yesAdvances in Electrical and Electronic Engineering, 2017
Application of equipment with power electronic converter interface such as distributed generation, FACTS and HVDC, is growing up intensively. On the other hand, various types of topologies have been proposed and each of them has some advantages ...
Masoud Jokar Kouhanjani, Ali Reza Seifi
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Online State Space Model Parameter Estimation in Synchronous Machines

open access: yesIranian Journal of Electrical and Electronic Engineering, 2014
The purpose of this paper is to present a new approach based on the Least Squares Error method for estimating the unknown parameters of the nonlinear 3rd order synchronous generator model.
Z. Gallehdari, M. Dehghani, K. Nikravesh
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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