Results 101 to 110 of about 19,149,312 (300)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Institutions Matter: Financial Supervision Architecture, Central Bank and Path Dependence. General Trends and the South Eastern European Countries [PDF]

open access: yes
We propose a path dependence approach to analyze the evolution of the financial supervisory architecture, focusing on the institutional role of the central bank, and then apply our framework to describe the institutional settings in a selected sample of ...
Marc Quintyn, Donato Masciandaro
core  

Discursive dissonance: Critical reflexivity for counselling supervision [PDF]

open access: yes, 2011
When practitioners and supervisors do not share the same counselling language or theoretical orientation, how is shared meaning achieved and relational connection sustained in supervision?
Esler, Ireni
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The Application of Hybrid Heat Insulation in Heat Supply Systems: Methods of Technical and Economic Substantiation

open access: yesЭкономика и управление, 2019
Heat supply systems are a crucial element of the utility system in Russian cities and towns. High system breakdown rates are largely a function of pipeline material, quality of installation, and the parameters of heat insulation that prevent heat loss ...
Vyacheslav P. Zakharov
doaj  

The results of epidemiological analysis of salmonellosis incidence in the Rostov region under current conditions

open access: yesМедицинский вестник Юга России
Objective: to study the features of the epidemic process of salmonella infection under current conditions. To establish a causal relationship between the incidence of salmonellosis and the functioning of public catering enterprises, which can form the ...
E. V. Kovalev   +10 more
doaj   +1 more source

The State’s Supervisory Mandate over Waqf Properties in the Modern Age [PDF]

open access: yesمجلة جامعة الأنبار للعلوم الإسلامية
                              Abstract:      This study discussed the state’s ...
Dr. Sultan Ali A Alqarawi -   +2 more
doaj   +1 more source

Bank Supervision and Corporate Finance [PDF]

open access: yes
We examine the impact of bank supervision on the financing obstacles faced by almost 5,000 corporations across 49 countries. We find that firms in countries with strong official supervisory agencies that directly monitor banks tend to face greater ...
Thorsten Beck   +2 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Incentive Problems in Banking Supervision: The European Case [PDF]

open access: yes
This paper discusses the incentive conflicts that arise in banking supervision in the EU in a principal-agent framework, where the regulator is the agent and the taxpayers is the principal.
Schüler, Martin
core  

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