Results 131 to 140 of about 1,232,717 (325)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Photoconductivity of the Polymer Layer with Resazurin Sodium at Two-photon Excitation [PDF]

open access: yesЖурнал нано- та електронної фізики, 2014
Experimental and theoretical studies of the photoconductivity of the polymer layer (PVP) with resazurin solution at two-photon excitation revealed that the two-quantum excitation in T(*)- state which corresponds to the quantum transition from a deep ...
T.M. Sakun
doaj  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Approximate power flow solutions‐based forecasting‐aided state estimation for power distribution networks

open access: yesIET Generation, Transmission & Distribution
This paper presents an approximate power flow model‐based forecasting‐aided state estimation estimator for power distribution networks subject to naive forecasting methods and nonlinear filtering processes.
Zhenyu Wang   +4 more
doaj   +1 more source

Representation of user transaction processing behavior with a state transition matrix [PDF]

open access: yesProceedings of the 24th conference on Winter simulation - WSC '92, 1992
William S. Keezer   +2 more
openaire   +1 more source

On the Numerical Computation of Transition Matrix pth Root

open access: yes, 2014
Transition matrices arise in a wide class of engineering problems especially in mathematical models using Markov chains. Usually they describe the transition probabilities of a vector state at time $t$ to the same state vector at time $t+\Delta t ...
POLITI, Tiziano, Popolizio M.
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Human Cancer Cells Express Slug-based Epithelial-Mesenchymal Transition Gene Signature Obtained in Vivo

open access: yes, 2011
The biological mechanisms underlying cancer cell motility and invasiveness remain unclear, although it has been hypothesized that they involve some type of epithelial-mesenchymal transition (EMT).
Rumjantseva Viktoria   +24 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

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