Results 111 to 120 of about 12,589,576 (355)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Ms. Foundation for Women, 2011 Annual Report [PDF]
Energized by New York, the Ms. Foundation is helping transform a regional win into victory nationwide. We were there to support DWU as it led the formation of the National Domestic Workers Alliance (NDWA), a coalition that now boasts 31 member groups ...
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
About “Paleozoic roots” of the oils of the eastern Ciscaucasia
The paper considers geochemical data on the biomarker composition of oils from the fields of the TerekCaspian oil and gas basin. Samples of oils from the fields of the main oil and gas bearing regions of the Eastern Ciscaucasia – Terek-Sunzha zone ...
N. Sh. Yandarbiev +3 more
doaj +1 more source
The Wage Penalty for State and Local Government Employees in New England [PDF]
The authors demonstrate that the average state or local government worker earns higher wages than the average private-sector worker—but only because they are, on average, older and substantially better educated.
Jeffrey Thompson, John Schmitt
core
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Unemployment Compensation (UC): Eligibility for Students Under State and Federal Laws [PDF]
[Excerpt] Unemployment Compensation (UC) is a joint federal-state program that provides income support payments to eligible workers who lose their jobs through no fault of their own. Federal law sets out broad guidelines with regard to how the UC program
Eder, Alan, Whittaker, Julie M
core +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Unions and Upward Mobility for Asian American and Pacific Islander Workers [PDF]
Asian Americans and Pacific Islanders (AAPIs) are, with Latinos, the fastest growing ethnic group in the U.S. workforce. In 2009, Asian American and Pacific Islanders were one of every 20 U.S. workers, up from one in 40 only 20 years earlier.
Hye Jin Rho, John Schmitt, Nicole Woo
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

