Results 51 to 60 of about 2,584,296 (324)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Fuzzy Logic: vulnerability of women who have sex with women to sexually transmitted infections [PDF]

open access: yesRevista Brasileira de Enfermagem
Objective: To describe the possibility of applying Fuzzy Logic in analyzing the vulnerability of Women Who Have Sex with Women to Sexually Transmitted Infections/HIV/AIDS. Methods: We developed a Fuzzy Logic system with 17 input variables and one output
Juliane Andrade   +5 more
doaj   +1 more source

Circuitree: A Datalog Reasoner in Zero-Knowledge

open access: yesIEEE Access, 2022
Driven by the increased consciousness in data ownership and privacy, zero-knowledge proofs (ZKPs) have become a popular tool to convince a third party of the truthfulness of a statement without disclosing any further information.
Tom Godden   +5 more
doaj   +1 more source

Schaefer's theorem for graphs [PDF]

open access: yes, 2015
Schaefer's theorem is a complexity classification result for so-called Boolean constraint satisfaction problems: it states that every Boolean constraint satisfaction problem is either contained in one out of six classes and can be solved in polynomial ...
Bodirsky, Manuel, Pinsker, Michael
core   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Modelling practical certainty and its link with classical propositional logic [PDF]

open access: yes, 2013
We model practical certainty in the language of accept & reject statement-based uncertainty models. We present three different ways, each time using a different nature of assessment: we study coherent models following from (i) favourability assessments, (
De Cooman, Gert, Van Camp, Arthur
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Enhancing automated financial statement analysis using fuzzy logic algorithms

open access: yesDiscover Computing
Financial statement analysis is crucial to organizational performance, but quantitative and rule-based methods often fail to capture nonlinear relationships, uncertainty, and rapidly changing market conditions.
Ruiyao Liu
doaj   +1 more source

Lom: discovering logic flaws within MongoDB-based web applications [PDF]

open access: yes, 2016
Logic flaws within web applications will allow malicious operations to be triggered towards back-end database. Existing approaches to identifying logic flaws of database accesses are strongly tied to structured query language (SQL) statement construction
Si, G-N   +6 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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