Results 41 to 50 of about 176,086,693 (264)

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Altered intrinsic brain activity in patients with familial cortical myoclonic tremor and epilepsy: An amplitude of low-frequency fluctuation study

, 2015
Purpose: To investigate localized cerebral function abnormalities in patients with familial cortical myoclonic tremor and epilepsy (FCMTE) using resting-state functional magnetic resonance imaging (fMRI). Methods: Seven patients with FCMTE from a Chinese
Bin, Yi, Yang, Zhenglin, Yao, Dezhong, Wang, Pu, Luo, Cheng, Dong, Li, Ma, Shi, Guo, Fuqiang, Guo, FQ (reprint author), Sichuan Acad Med Sci, Dept Neurol, Chengdu, Sichuan, Peoples R China.   +8 more
core   +1 more source

Altered dynamic spontaneous neural activity in minimal hepatic encephalopathy

Frontiers in Neurology, 2022
Background and aims:Abnormal regional neural activity has been identified by the analysis of the static amplitude of low-frequency fluctuation (ALFF) in the setting of minimal hepatic encephalopathy (MHE). Brain activity is highly dynamic.
Jie-Ru Guo, Jia-Yan Shi, Qiu-Yi Dong, Yun-Bin Cao, Dan Li, Hua-Jun Chen   +5 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Searchlight classification based on Amplitude of Low Frequency Fluctuation and functional connectivity in individuals with obsessive-compulsive symptoms

, 2019
Introduction: Investigating obsessive-compulsive symptoms in subclinical populations provides a useful framework for understanding the early development of obsessive-compulsive spectrum disorders.
Sørensen, TA, Chan, RCK, Chan, Raymond C.K., Cheung, Eric F.C., Zhang, Rui Ting, Wang, Yong-ming, Cai, Xin Lu, Cai, Xin-lu, Wang, YM, Møller, Arne, Madsen, KH, Chan, Raymond C. K., Wang, Y, Cheung, EFC, Sorensen, Thomas Alrik, Zhang, Rui-ting, Moller, Arne, Wang, Yong Ming, Wang, Yi, Cai, XL, Sørensen, Thomas Alrik, Sørensen, Thomas Alrik; id_orcid, Madsen, Kristoffer Hougaard, Cheung, Eric F. C., Zhang, RT, Møller, A   +25 more
core   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Low Frequency Fluctuation in FET's [PDF]

The Low frequency fluctuation in the drain current of a field effect transistor is experimentally analysed. It is shown to be induced by the ambient temperature fluctuation.
ハシグチ, スミヒサ, Kurita, Kaoru, 伊藤, 郁義, Hashiguchi, Sumihisa, 栗田, 薫, Ito, Fumiyoshi, 橋口, 住久   +6 more
core   +1 more source

Frequency-dependent changes in the amplitude of low-frequency fluctuations in patients with Wilson’s disease: a resting-state fMRI study [PDF]

, 2017
To investigate the frequency-dependent changes in the amplitude of low-frequency fluctuations (ALFF) in patients with Wilson's disease (WD). Resting-state function magnetic resonance imaging (R-fMRI) were employed to measure the amplitude of ALFF ...
Yongqiang Yu, Huang, Chang-Bing, Chen, Siyi, Yu, Yongqiang, Siyi Chen, Chang-Bing Huang, Hu, Xiaopeng, Qian, Yinfeng, Yinfeng Qian, Huang, Changbing, Xiaopeng Hu   +10 more
core   +1 more source

Functional Connectivity Dynamics Altered of the Resting Brain in Subjective Cognitive Decline

Frontiers in Aging Neuroscience, 2022
BackgroundSubjective cognitive decline (SCD) appears in the preclinical stage of the Alzheimer's disease continuum. In this stage, dynamic features are more sensitive than static features to reflect early subtle changes in functional brain connectivity ...
Yi-Chia Wei, Yi-Chia Wei, Yi-Chia Wei, Yi-Chia Kung, Wen-Yi Huang, Wen-Yi Huang, Wen-Yi Huang, Chemin Lin, Chemin Lin, Chemin Lin, Yao-Liang Chen, Yao-Liang Chen, Chih-Ken Chen, Chih-Ken Chen, Chih-Ken Chen, Yu-Chiau Shyu, Yu-Chiau Shyu, Ching-Po Lin   +17 more
doaj   +1 more source