Results 91 to 100 of about 508,047 (264)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Automated Intel SGX Integration for Enhanced Application Security
Nowadays, many chip manufacturers offer various Trusted Execution Environment (TEE) implementations to protect the critical data and the algorithms in hardware.
Leonardo Regano, Daniele Canavese
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Static Analysis of Wooden Beams Strengthened with FRCM-PBO Composite in Bending. [PDF]
Sokołowski PK, Kossakowski PG.
europepmc +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Deploying sensors to target locations using UAV platforms can effectively address the issue of limited aerial endurance in micro-UAVs. This paper introduces a launch method based on the crossbow principle, which is capable of concealing the deployment of
Yanan He +5 more
doaj +1 more source
Nonlocal Strain Gradient Model for the Nonlinear Static Analysis of a Circular/Annular Nanoplate. [PDF]
Sadeghian M, Palevicius A, Janusas G.
europepmc +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Automated vulnerability discovery method for 5G core network protocol
With the widespread development of fifth-generation (5G) mobile communication technology, concerns regarding 5G network security have also increased.Blackbox fuzzing is a commonly used method for automated vulnerability discovery in software security ...
Peixiang WU +4 more
doaj

