Results 101 to 110 of about 640,088 (259)

Static code analysis with SonarQube and Large Language Models

openLa tesi affronta il tema della sicurezza informatica con un focus specifico sull'analisi statica del codice sorgente. In particolare, viene esplorato l'utilizzo di strumenti come SonarQube e Semgrep per identificare vulnerabilità e cattive pratiche ...
EL MOUTAREN, BILAL
core  

Using Counts as Heuristics for the Analysis of Static Models

, 1998
The upstream activities of software development are often viewed as both the most important, in terms of cost, and the yet the least understood, and most problematic, particularly in terms of satisfying customer requirements.
Phalp, Keith T., Counsell, Steve J., Chen, Liguang, Shepperd, M.   +3 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Renraku — the One Static Analysis Model to Rule Them All

, 2017
Most of the static analyzers are monolithic applications that define their own ways to analyze source code and present the results. Therefore aggregating multiple static analyzers into a single tool or integrating a new analyzer into existing tools ...
Tymchuk, Yuriy, Mohammad Ghafari, Ghafari, Mohammad, Nierstrasz, Oscar Marius, Oscar Nierstrasz, Yuriy Tymchuk   +5 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Abstraction-Based Static Analysis of Buffer Overruns in C Programs

, 2003
Bounds violations or buffer overruns have historically been a major source of defects in software systems, making bounds checking a key component in practical automatic verification methods.
Srinivasa, Gopal Ranganatha
core  

Numerical static analysis with Soot

, 2013
Numerical static analysis computes an approximation of all the possible values that a numeric variable may assume, in any execution of the program. Many numerical static analyses have been proposed exploiting the theory of abstract interpretation, which ...
Francesca Scozzari, Simone Di Nardo Di Maio, DI NARDO DI MAIO, SIMONE, AMATO, Gianluca, SCOZZARI, Francesca, Gianluca Amato   +5 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source