Results 91 to 100 of about 7,401,358 (355)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Cancer Management and Research, 2019 Yue Hu,1,2,* Jingsi Mei,1,2,* Xiaofang Jiang,1,2 Ran Gu,1,2 Fengtao Liu,1,2 Yaping Yang,1,2 Hongli Wang,1,2 Shiyu Shen,1,2 Haixia Jia,3 Qiang Liu,1,2 Chang Gong1,21Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation ...
Hu Y +10 more
doaj
Direct Measurement of Dynamics in Road Bridges Using a Bridge Weigh-In-Motion System
The Baltic Journal of Road and Bridge Engineering, 2013 A method is presented of measuring a bridge’s characteristic allowance for dynamic interaction in the form of Assessment Dynamic Ratio. Using a Bridge Weigh-in-Motion system, measurements were taken at a bridge in Slovenia over 58 days.
Eugene J. OBrien +3 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Stability assessment method based on actual measurements for a cable-driven continuum robot
Nihon Kikai Gakkai ronbunshuIn order to experimentally determine the controlled variable values realizing a quasi-zero stiffness of a cable driven continuum robot, this paper presents an experimental method for quantitatively and accurately assessing the stability of a robot in a ...
Ryota SHIOYA, Yukio TAKEDA
doaj +1 more source
RIMCIS, 2018 The present study examined the association between static assessment, dynamic assessment and fluid intelligence. A pool of 109 students majoring in English Language Teaching and Translation Studies took part in the study.
Ghasem Modarresi, Ali Jeddy
doaj +1 more source
Upper-surface-blowing flow-turning performance [PDF]
Jet exhaust flow-turning characteristics were determined for systematic variations in upper-surface blowing exhaust nozzles and trailing-edge flap configuration variables from experimental wind-off (static) flow studies. For conditions with parallel flow
Phelps, A. E., III, Sleeman, W. C., Jr.
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A unique facility for V/STOL aircraft hover testing [PDF]
The Langley Impact Dynamics Research Facility (IDRF) was modified to obtain static force and moment data and to allow assessment of aircraft handling qualities during dynamic tethered hover flight. Test probe procedures were also established. Static lift
Culpepper, R. G. +3 more
core +1 more source