Results 101 to 110 of about 7,401,358 (355)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

A Modelling Approach for Evaluating Agri-Environmental Policies at Sector Level [PDF]

, 2008
This paper presents a new approach to evaluate the cost effectiveness of agri-environmental policies at sector level. Policy uptake, cumulative environmental effects and public expenditure are identified as the main determinants of cost-effectiveness. On
Lampkin, N. H., Nemecek, T, Sanders, J., Schader, C., Stolze, M.   +4 more
core  

Dynamic assessment of word learning skills of preschool children with primary language impairment [PDF]

, 2013
Dynamic assessment has been shown to have considerable theoretical and clinical significance in the assessment of socially disadvantaged and culturally and linguistically diverse children.
Bain B. A., Bernard Camilleri, Brown A. L., Camilleri B., Camilleri B., Carey S, Clark E. V, Dale P. S., Desmarais C., Desmarais C., Dollaghan C, Dollaghan C, Dunn L., Elliott C. D, Fagundes D. D., Feuerstein R, Gutierrez-Clellen V. F., Harris M, Hasson N., Haywood C. H., Haywood C. H., Heibeck T. H., Hoben K., James Law, Law J., Law J., Olswang L. B., Olswang L. B., Peña E., Peña E., Peña E., Peña E., Peña E., Reilly S., Rice M. L., Rice M. L., Rice M. L., Rutter M, Sternberg R. J., Tomblin J. B, Vygotsky L. S, Wright D. B, Zhang X.   +42 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Exact Inference Techniques for the Analysis of Bayesian Attack Graphs [PDF]

, 2016
Attack graphs are a powerful tool for security risk assessment by analysing network vulnerabilities and the paths attackers can use to compromise network resources.
Barrère, Martín, Lupu, Emil, Muñoz-González, Luis, Sgandurra, Daniele   +3 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Exploratory rasch analysis of a static-99R clinical cohort assessment.

PLoS ONE
Modern test theory supplements the more prevalent classic methods for assessing test properties. However, such an assessment of the commonly used sexual recidivism risk assessment instrument, Static-99R, has yet to be attempted.
Christian Baudin, Anna Grimby-Ekman, Thomas Nilsson, Märta Wallinius, Peter Andiné   +4 more
doaj   +1 more source

Developing Seismic Risk Prediction Functions for Structures

Shock and Vibration, 2018
The paper presents the development of a nonlinear static displacement-based methodology for seismic risk assessment and loss estimation of stone masonry building stock of Pakistan.
Naveed Ahmad, Qaisar Ali, Muhammad Adil, Akhtar Naeem Khan   +3 more
doaj   +1 more source

Theoretical and experimental structural studies of historical Latin-American laminated planked timber arches

, 2012
This article describes a first group of theoretical and experimental works undertaken at the Polytechnic University of Madrid. One major purpose is to obtain a structural model for the assessment of historical Latin-American vertically laminated planked ...
Arce Blanco, Marina, Díez Barra, Rafael, Fernández Cabo, José Luis, Hurtado Valdez, Pedro   +3 more
core  

Analysis of a rapid load test on an instrumented bored pile in clay [PDF]

, 2006
Rapid load testing methods for piled foundations are generally easier and quicker to mobilise than classic static tests, and are less complex to analyse than dynamic load tests.
A. F. L. Hyde, Bell A., Berridge N. G., Borghi X., British Standards Institution, Brown M. J., Delpak R., Dunnicliff J., Gibson G. C., Hird C. C., Holeyman A. E., Hyde A. F. L., Institution of Civil Engineers, Kusakabe O., M. J. Brown, Marsland A., McVay M. C., Middendorp P., Middendorp P., Middendorp P., Nishimura S., Powell J. J. M., Randolph M. F., Randolph M. F., Smith E. A. L., Tatsuoka F., Taylor P. T., W. F. Anderson, Weltman A. J.   +28 more
core   +2 more sources