Results 141 to 150 of about 7,401,358 (355)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Economic consequences of intifada: a sequel [PDF]
We give an assessment of the loss in the nominal gross domestic product (GDP) and nominal gross national income (GNI) due to twenty- seven months of intifada.
Boer, P.M.C. de, Missaglia, M.
core +1 more source
Seismic assessment of the Qutb Minar in Delhi, India [PDF]
, 2008 The present paper describes the seismic assessment of the Qutb Minar in Delhi, India. Three models with different levels of complexity and simplifications were developed.
Lourenço, Paulo B. +2 more
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
CHOICE AND TEMPORAL WELFARE IMPACTS: DYNAMIC GEV DISCRETE CHOICE MODELS [PDF]
Welfare economics is often employed to measure the impact of economic policies or externalities. When demand is characterized by discrete choices, static models of consumer demand are employed for this type of analysis because of the difficulty in ...
Adamowicz, Wiktor L. +2 more
core +1 more source
Quantitative Assessment of the Impact of Automatic Static Analysis Issues on Time Efficiency [PDF]
, 2011 Background: Automatic Static Analysis (ASA) tools analyze source code and look for code patterns (aka smells) that might cause defective behavior or might degrade other dimensions of software quality, e.g. efficiency.
Morisio, Maurizio +2 more
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Al-Khawarizmi Engineering Journal, 2009 This paper presents a robust algorithm for the assessment of risk priority for medical equipment based on the calculation of static and dynamic risk factors and Kohnen Self Organization Maps (SOM).
Nebras H. Ghaeb +2 more
doaj +2 more sources
Assessment of ChatGPT for Engineering Statics Analysis
Large language models (LLMs) such as OpenAI's ChatGPT hold potential for automating engineering analysis, yet their reliability in solving multi-step statics problems remains uncertain. This study evaluates the performance of ChatGPT-4o and ChatGPT-o1-preview on foundational statics tasks, from simple calculations of Newton's second law of motion to ...
Hope, Benjamin +3 more
openaire +2 more sources