Results 61 to 70 of about 2,035,474 (280)
Synchronized stationary clouds in a static fluid
Physics Letters B, 2018 The existence of stationary bound states for the hydrodynamic velocity field between two concentric cylinders is established. We argue that rotational motion, together with a trapping mechanism for the associated field, is sufficient to mitigate energy ...
Carolina L. Benone +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Fluid-particle dynamics of nasal drug delivery in a realistic human airway lung model
, 2022 Nasal drug delivery provides a rapid onset of therapeutic effects due to the nasal route's large surface area, high blood flow, and ease of accessibility.
Francis, Isabella +3 more
core
Numerical simulation of granular mixing in static mixers with different geometries
Advances in Difference Equations, 2019 A static mixer is a fidelity engineered device for the continuous mixing of fluid/solid materials. To meet the requirements for mixing purpose, a proper design of the static mixer is important.
Noraphon Bunkluarb +3 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Static-Analysis-study/home: v1.0.0
<p><strong>Full Changelog</strong>: https://github.com/Static-Analysis-study/home/commits/v1.0.0</p ...
Static-Analysis-study
core +1 more source
Analytical studies on the hoop conjecture in charged curved spacetimes
European Physical Journal C: Particles and Fields, 2019 Recently, with numerical methods, Hod clarified the validity of Thorne hoop conjecture for spatially regular static charged fluid spheres, which were considered as counterexamples against the hoop conjecture.
Yan Peng
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source