Results 201 to 210 of about 270,891 (266)

Dynamic nested hierarchies: self-evolving machine learning architectures for lifelong learning. [PDF]

Front Artif Intell
Jafari AA, Ozcinar C, Anbarjafari G.
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Static-electricity-induced luminescence trajectory tracking: A paradigm for noncontact human-machine interaction in dark environments. [PDF]

Sci Adv
Ou J, Fang S, Zhang T, Cheng H, Liu T, Yu J, Xie R, Yan W, Zhao D, Qiu M, Yuan M, Wang L.   +11 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Mixed Forecast of Air Quality Index with a Bibranch Parallel Architecture Considering Seasonal Heterogeneity. [PDF]

Entropy (Basel)
Zeng H, Liu Y, Dai H, Zhao X, Tian N.
europepmc   +1 more source

Strengthening the Substrates of Wood Single Lap Joints Using a Novel Hot-Melt Film Adhesive to Mitigate Delamination. [PDF]

Materials (Basel)
Ribeiro FCC, Jalali S, Rodrigues VCMB, Carbas RJC, Marques EAS, Sun F, da Silva LFM.   +6 more
europepmc   +1 more source

MoC-TSCH: multi-objective MILP-based TSCH mobility optimization for network coverage and connectivity in IIoT. [PDF]

Sci Rep
Mulatu AN, Zennaro M, Gared F, Prabhakar TV.   +3 more
europepmc   +1 more source