Results 41 to 50 of about 7,177 (262)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Green-RPL: An Energy-Efficient Protocol for Cognitive Radio Enabled AMI Network in Smart Grid

open access: yesIEEE Access, 2018
With the capacity of achieving spectrum efficient wireless communications, cognitive radio enabled advanced metering infrastructure (CR-AMI) networks are expected to enhance the efficiency and practicability of future smart grids.
Zhutian Yang   +3 more
doaj   +1 more source

Intersection Routing Based on Fuzzy Multi-Factor Decision for VANETs

open access: yesApplied Sciences, 2020
Vehicular ad hoc network (VANET) is a special form of mobile ad hoc network (MANET), which plays a key role in the intelligent transportation system (ITS).
Zhenbo Cao   +4 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Delay Efficient Backpressure Routing in Wireless Ad Hoc Networks

open access: yesEAI Endorsed Transactions on Mobile Communications and Applications, 2014
Packet scheduling/routing in wireless ad hoc networks is a fundamental problem for ad hoc networking. Backpressure routing is a solid and throughput optimal policy for such networks, but suffers from increased delays.
Leandros A. Maglaras, Dimitrios Katsaros
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Design on routing optimization algorithm based on complex network

open access: yesMATEC Web of Conferences, 2018
In order to solve the problem of information flow network transmission and congestion control in complex internet networks, A new and complicated routing network algorithm based on network evolution simulation model is proposed, An improved method is ...
Guo Yang, Zhou Jinhe
doaj   +1 more source

MOBILITY PATTERN FREE DYNAMIC AND EFFECTIVE LOCATION UPDATE IN MANET

open access: yesICTACT Journal on Communication Technology, 2017
The beaconing approach is the key function in geographic routing to disseminate the location. However, the node mobility is a prominent challenge to the beacon based location broadcasting schemes resulting in high routing overhead.
N Palanisamy, V Muralibhaskaran
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

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