Results 61 to 70 of about 223,206 (264)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Numerical Simulation of Material Strength Deterioration due to Pitting Corrosion [PDF]
, 2014 Pitting corrosion is an insidious form of localized corrosion affecting characteristics of various engineering metallic alloys. Currently very limited literature exists with regard to systematic characterization of pitted surfaces or the efficient use of
Salonitis, Konstantinos +3 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Dynamic tensile behaviour and crack propagation of coal under coupled static-dynamic loading
International Journal of Mining Science and Technology, 2020 The fracture behaviour and crack propagation features of coal under coupled static-dynamic loading conditions are important when evaluating the dynamic failure of coal.
Xianjie Hao +6 more
doaj +1 more source
Investigating the effects of typical rowing strength training practices on strength and power development and 2,000m rowing performance [PDF]
, 2016 This study aimed to determine the effects of a short-term, strength training intervention, typically undertaken by club-standard rowers, on 2,000 m rowing performance and strength and power development.
Thompson, Kevin Grant +11 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
The effect of voids on the flexural fatigue properties of carbon/epoxy composites [PDF]
, 2010 The role of voids in composite failures has not been well understood or been characterized. This study presents the result of an investigation aimed at examining the mechanical behaviour of unidirectional carbon fibre-reinforced polymer matrix materials ...
Suhot, Mohamed Azlan
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Stress State and Strength of the Piezoceramics at Static Load [PDF]
The strength of piezoelectric transducer at static loading and vibrations was investigated. The theoretical model of strength for piezoceramics stripe glued to structural element was developed.
Pavelko, Igors +4 more
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