Results 121 to 130 of about 9,656 (253)

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu   +4 more
wiley   +1 more source

A Perspective of Multi‐Reflecting TOF MS

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Time‐of‐flight mass spectrometry (TOF MS) excels in rapid and high‐sensitivity analysis, making it a cornerstone of analytical chemistry. But as sample complexity explodes in omics studies, so does the need for higher resolving power to ensure accurate results.
A. N. Verenchikov   +3 more
wiley   +1 more source

Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei   +7 more
wiley   +1 more source

Aberrant Beta‐Band Network Alteration Preceding Freezing of Gait in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Freezing of gait (FOG) is a debilitating motor symptom observed in the advanced stages of Parkinson's disease (PD), characterized by an abrupt inability to initiate or continue forward walking. Whole‐brain functional connectivity analysis has shown promise in elucidating the underlying pathophysiology and identifying potential ...
Yanqiu Tian   +3 more
wiley   +1 more source

Angle stability improvement using optimised proportional integral derivative with filter controller. [PDF]

open access: yesHeliyon
Khawaja AW   +6 more
europepmc   +1 more source

New Opportunities For the Integration of Artificial Intelligence With Materials Science: From Large Language Models to Embodied Large Models

open access: yesMaterials Genome Engineering Advances, EarlyView.
This review first introduces the diversified applications of large language models in materials discovery. Subsequently, the evolution of autonomous experimentation platforms empowered by large language models is analyzed. Finally, four key future research interests are proposed to develop embodied large models for driving autonomous experimentation ...
Zhen Song   +6 more
wiley   +1 more source

Spatiotemporal Encoding With Nonlinear Gradient Hardware Using Pulseq: From Principles to Practical Demonstration

open access: yesMagnetic Resonance in Medicine, EarlyView.
Purpose Provide the theoretical foundation and the first practical demonstration of spatiotemporal encoding (SPEN) using additional nonlinear gradient hardware. Methods The quadratic phase profile can be generated either by a chirped‐RF pulse combined with a constant gradient or, directly, by a quadratic gradient pulse.
Andreas Holl   +8 more
wiley   +1 more source

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