Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Effectiveness of post-grouting on the vertical response improvement for extra-long bored piles: case studies on field tests. [PDF]
Xie X, Hu T, Wang L, Zhou F, Wan Z.
europepmc +1 more source
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Acute neuromechanical effects of static and PNF hamstring stretching on explosive power and balance. [PDF]
Tai WH +5 more
europepmc +1 more source
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Dynamic Compressive Mechanical Properties of Polyvinyl Alcohol Fiber-Reinforced Geopolymer Composites. [PDF]
Li M, Liu Q, Tan Y, Dai F, Wang S.
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Relationship between scapular dyskinesis test and lateral scapular slide test in office workers with chronic neck pain: a cross-sectional study. [PDF]
Moon SE, Kim YK.
europepmc +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Calibration of the Karagozian & Case model for compression and tensile tests of a 3,4-dinitropyrazole-based melt-cast explosive. [PDF]
Xu Y +5 more
europepmc +1 more source

