Results 151 to 160 of about 36,758 (301)

Machine Learning‐Driven Prediction of Microplastic Aging Processes and Environmental Risk Assessment Across Multi‐Media Systems

Advanced Science, EarlyView.
This perspective proposes a cohesive machine learning strategy to decode microplastic aging. It advocates for Federated Learning to dismantle global data silos and introduces the TRACE framework (TRansport, Aging, Corona, Ecotoxicity). By integrating physics‐informed modeling with causal discovery, this approach bridges the laboratory‐field gap to ...
Yaping Lyu, Xinran Qiu, Xing Li, Tianhuan Yang, Xuetao Guo, Hao Qiu, Peng Zhang   +6 more
wiley   +1 more source

Boronic acid affinity media conjugating with PEG enable precise pH-responsive HPLC separation of glycoproteins depending on differences of sugar chains. [PDF]

Sci Rep
Koda K, Konishi-Yamada S, Kubo T.
europepmc   +1 more source

Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing

Advanced Science, EarlyView.
A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo, Yuyao Qu, Zhengyan Ye, Zheng Li, Yuanyan Zhang, Longjiong Luo, Shaokang Li, Wei Zhao, Ming Wang, Ralph Bock, Jianmin Wan, Junjie Tan   +11 more
wiley   +1 more source

Method Development and Validation for the Simultaneous Analysis of Miconazole Nitrate, Hydrocortisone and Chlorocresol in a Pharmaceutical Topical Cream by Reverse Phase Liquid Chromatography. [PDF]

Anal Sci Adv
Mukaratirwa-Muchanyereyi N, Chihiya P, Nyoni S.   +2 more
europepmc   +1 more source

Computation‐Guided Control of Excited‐State Deactivation through Modulation of Conical‐Intersection Accessibility by Donor–Acceptor Asymmetry in Bridged Stilbene AIE Luminogens

Advanced Science, EarlyView.
Donor–acceptor asymmetry modulates conical‐intersection accessibility and topology in bridged stilbenes, providing mechanistic insight into excited‐state deactivation and aggregation‐induced emission (AIE). ABSTRACT A computation‐guided investigation of asymmetric donor–acceptor bridged stilbenes reveals structure–property relationships governing ...
Takuya Tanaka, Satoshi Suzuki, Hirosato Koyanagi, Kiyoshi Miyata, Riki Iwai, Kazunobu Igawa, Ken Onda, Ben Zhong Tang, Gen‐ichi Konishi   +8 more
wiley   +1 more source

Phase-Specific Parameter Estimation in Chiral HPLC Using 1-Site, 2-Site Stochastic Models, and Unified Equation Approach. [PDF]

Anal Chem
Mirzahosseini A, Mhammad A, Dombi G, Balogh B, Sepsey A, Pálla T, Horváth S, Tóth E, Szabó ZI, Németh G, Felinger A, Trapp O, Tóth G.   +12 more
europepmc   +1 more source

Stationary phase optimized selectivity supercritical fluid chromatography (SOS-SFC)

, 2013
In stationary phase optimized selectivity liquid chromatography (SOS-LC) the stationary phase becomes a tunable parameter by connecting column segments with variable lengths of different stationary phases. An optimization procedure and algorithm based on
Delahaye, SanderUGent002004434470802000744613979291868052040C3552-F0EE-11E1-A9DE-61C894A0A6B4, Delahaye, Sander, Lynen, Frederic, Lynen, FredericWE078010011330380000-0002-4690-7690F52D4724-F0ED-11E1-A9DE-61C894A0A6B4   +3 more
core  

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source

Propionic Acid Outperforms Formic and Acetic Acid in MS Sensitivity for High-Flow Reversed-Phase LC-MS Bottom-Up Proteomics. [PDF]

Anal Chem
Starovoit MR, Jadeja S, Kupčík R, Vatić S, Rasl J, Demir D, Novák P, Braswell C, Orsburn BC, Lenčo J.   +9 more
europepmc   +1 more source

Retention and selectivity effects of coating octadecylsilica stationary phases with low molecular weight alcohols in reversed-phase liquid chromatography using water as mobile phase

, 1998
A simple but useful experimental method for observation of the effects of organic modifiers in the stationary phase in reversed-phase liquid chromatography (RPLC) is reported.
Hu, W (15482138), Paul Haddad (14738197)
core