Nucleation Kinetics Reveals a Distinct Biological Function Space of Biomolecular Condensates
Advanced Science, EarlyView.This study utilizes microfluidics to quantify the nucleation rates of dense liquid phases within dilute solutions and of the reverse process, in which dilute voids nucleate inside condensates. The interfacial tension is identified as the key determinant of both processes.
Leif‐Thore Deck +5 more
wiley +1 more source
Advances in Analysis of Therapeutic Oligonucleotides with Chromatography Coupled to Mass Spectrometry. [PDF]
Anal ChemAl Bardawil S, Barthélémy P, Ferey L.
europepmc +1 more source
Advanced Science, EarlyView.Inspired by the mimosa, this study develops a flexible triboelectric nanogenerator with a novel microneedle array and battery‐mimetic architecture. The device introduces a spontaneous charge self‐regulation mechanism that confines the electric field below the air breakdown threshold, and achieves an outstanding charge density of 396.50 µC m−2 ...
Hanpeng Gao +7 more
wiley +1 more source
Comprehensive Chemometric and Chromatographic Investigation of Lipophilicity of Biologically Active Androstane-3-Oxime Derivatives Across Diverse UHPLC Systems. [PDF]
Pharmaceuticals (Basel)Kovačević SZ +4 more
europepmc +1 more source
Advanced Science, EarlyView.AAA ABSTRACT Protein glycosylation and phosphorylation are critical post‐translational modifications (PTMs) governing nearly all cellular functions, yet their analysis remains challenging due to reliance on costly and unsustainable enrichment materials.
Jiaying Li +9 more
wiley +1 more source
A GC-MS Database of Nitrogen-Rich Volatile Compounds. [PDF]
ToxicsSholokhova AY +3 more
europepmc +1 more source
Millimeter‐Scale Dual‐Opposing RNA‐Gradient Hydrogel for Interfacial Gene Silencing
Advanced Science, EarlyView.A branched microfluidic platform enables the fabrication of millimeter‐scale hydrogels with dual‐opposing RNA‐gradients for precise spatial control of cell gene expression. This device allows for the generation of multiple constructs at once, offering potential for future engineering of complex tissue interfaces with improved physiological relevance ...
Tyler Hoffman +11 more
wiley +1 more source
Unsupervised Hierarchical Symbolic Regression for Interpretable Property Modeling in Complex Multi-Variable Systems. [PDF]
Adv Sci (Weinh)Lou S, Liu C, Zhang D, Chen Y, Mo F.
europepmc +1 more source
Advanced Science, EarlyView.The design employs heterogeneous wettability surfaces that construct stable oil‐water interfaces to achieve robust and rapid reversible adhesion. Linear enhancement of adhesion strength is realized through multi‐interface patterning. This adhesive enables rapid on‐demand detachment within five seconds via voltage‐induced electrolysis, offering a level ...
Xiaokai Li +11 more
wiley +1 more source
Total Breakthrough Strategy in Hydrophilic Interaction Chromatography for IP-RPLC × HILIC Separation of Oligonucleotides. [PDF]
J Sep SciAebischer MK, Abdurahman Y, Guillarme D.
europepmc +1 more source