Results 191 to 200 of about 4,812,323 (280)

Dual Nickel/Photoredox‐Catalyzed Regio‐ and Enantioselective Alkenylation of Epoxides

Advanced Science, EarlyView.
Ni/photoredox‐catalyzed stereoconvergent cross‐electrophile coupling of racemic epoxides with alkenyl bromides is described, affording β‐alkenyl products with up to 95% ee, excellent E‐selectivity, and complete regiocontrol. These versatile intermediates enable diverse chiral synthons; mechanistic studies suggest a halide ring‐opening followed by ...
Hongyan Lan, Shengzhou Jin, Zhao‐Dong Xu, Guigen Li, Dingyi Wang   +4 more
wiley   +1 more source

Condition-Specific LC Retention Time Prediction: Feature-Selected QSRR Versus Pretrained Graph Isomorphism Network Transfer Learning. [PDF]

Int J Mol Sci
Szucs R, Sýkorová E, Boháčová I, Neri I, Morgan LM, Moriarty M, Hanna-Brown M.   +6 more
europepmc   +1 more source

Comparison of the peak resolution and the stationary phase retention between the satellite and the planetary motions using the coil satellite centrifuge with counter-current chromatographic separation of 4-methylumbelliferyl sugar derivatives. [PDF]

J Chromatogr A, 2017
Shinomiya K, Zaima K, Harada Y, Yasue M, Harikai N, Tokura K, Ito Y.   +6 more
europepmc   +1 more source

Imperfect Oriented Attachment of Gold Nanoparticles

Advanced Science, EarlyView.
The cover illustrates the imperfect oriented attachment of gold nanoparticles in liquid, as revealed by in situ liquid‐phase transmission electron microscopy. Triggered by the abrupt collapse of the interfacial hydration layer, two misoriented nanoparticles undergo a kinetically driven “jump‐to‐coalescence”.
Fangjie Meng, Peng Hu, Yongzhao Zhang, Gengshuo Zhang, Jiaqi Zhang, Ronghan Wei, Wen Wang, Shaobo Cheng   +7 more
wiley   +1 more source

From the Gut to the Brain: Modeling Intestinal Absorption and Assessing Blood-Brain-Barrier Permeability of Small-Molecule Drugs by IAM Chromatography. [PDF]

ACS Omega
Simić S, Kalaba P, Wackerlig J, Langer T.   +3 more
europepmc   +1 more source

Mesoporous PU/PEDOT:PSS Electrodes Reveal Population‐Level Stochastic Bioelectrical Dynamics in Marine Diatoms

Advanced Science, EarlyView.
Mesoporous mixed ionic‐electronic PU/PEDOT: PSS electrodes enable label‐free detection of stochastic extracellular bioelectrical dynamics in living Phaeodactylum tricornutum. Living diatoms actively modulate interfacial ionic dynamics, establishing stochastic electrochemical noise as a sensitive probe of microbial bioelectrochemical activity and a new ...
David M. S. Silva, Felipe L. Bacellar, Raquel Amaral, Louis‐Josselin Lavier‐Aydat, Luísa Cortes, Kamal Asadi, Leïla Tirichine, Paulo R. F. Rocha   +7 more
wiley   +1 more source

A highly aqueous HPLC-PDA method for the assay of gabapentin and pregabalin: applications in pharmaceutical analysis, dissolution testing, and forensic screening. [PDF]

Front Chem
Alamri FM, Sahlabji T, Alshehri YM, Al Othaim IA, Aldawasri FS, Idris AM.   +5 more
europepmc   +1 more source

A Modular Variable Stiffness Co‐Bot System Achieving Tasks Flexibility and Contact Compliance

Advanced Science, EarlyView.
Bio‐inspired antagonistic compliance enables a modular rigid‐soft co‐bot platform with variable stiffness for safe human‐robot interaction (HRI): Standardized interfaces support application‐driven configurations with tailored DoFs, workspace, and stiffness range, making the system suited to HRI and low‐volume automation.
Wenlong Gaozhang, Yue Li, Jialei Shi, Yaxi Wang, Kaspar Althoefer, Agostino Stilli, Helge A. Wurdemann   +6 more
wiley   +1 more source

Determination of the surface properties and isomer pair separation powers of benzoin gums using inverse gas chromatography. [PDF]

Sci Rep
Erdogan Cakar A.
europepmc   +1 more source

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

Advanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang, Shuiping Fu, Ye Xu, Jia Gao, Jiwei Ren, Xu Yang, Hesong Xu, Ge Sun, Yanjie Li, Yanlin Wang, Lu Jin, Peijuan Chen, Ying Xu, Jianhao Li, Hua Lin, Chujiao Hu, Kaixian Chen, Huan Xiong, Cheng Luo, Shijie Chen   +19 more
wiley   +1 more source