Results 41 to 50 of about 5,042,699 (188)

Development and Validation of Retention Models in Supercritical Fluid Chromatography for Impregnation Process Design

Applied Sciences, 2021
The retention factor is the key quantity for the thermodynamic analysis of the retention mechanism in chromatographic experiments. In this work, we measure retention factors for moderately polar solutes on four silica-based porous matrices as stationary ...
Miaotian Sun, Zeynep Ülker, Zhixing Chen, Sivaraman Deeptanshu, Monika Johannsen, Can Erkey, Pavel Gurikov   +6 more
doaj   +1 more source

Comparison of Various Chromatographic Systems for Identification of Vortioxetine in Bulk Drug Substance, Human Serum, Saliva, and Urine Samples by HPLC-DAD and LC-QTOF-MS

Molecules, 2020
Background: Determination of psychotropic drugs in clinical study is significant, and the establishment of methodologies for these drugs in biological matrices is essential for patients’ safety.
Anna Petruczynik, Karol Wróblewski, Krzysztof Wojtanowski, Tomasz Mroczek, Dariusz Juchnowicz, Hanna Karakuła-Juchnowicz, Tomasz Tuzimski   +6 more
doaj   +1 more source

Silica-Based Stationary Phase with Surface Bound N-Acetyl-glucosamine for Hydrophilic Interaction Liquid Chromatography

Molecules, 2023
A hydrophilic silica-based stationary phase with surface bound N-acetylglucosamine (GlcNAc-silica) was prepared in house and characterized physically via Fourier transform infrared (FTIR) analysis and thermogravimetric analysis (TGA) and ...
Vaithilingam Rajendiran, Ziad El Rassi
doaj   +1 more source

Prediction of Bleeding via Simulation of Hydrodynamics in Centrifugal Partition Chromatography

Separations
Centrifugal Partition Chromatography (CPC) utilizes a two-phase liquid–liquid system as mobile and stationary phases. During operation, the latter continuously drains out of the rotor, despite it being in fact stationary, leading to decreasing separation
Felix Buthmann, Sophia Volpert, Jörg Koop, Gerhard Schembecker   +3 more
doaj   +1 more source

In-Column Dehydration Benzyl Alcohols and Their Chromatographic Behavior on Pyridinium-Based Ionic Liquids as Gas Stationary Phases

Molecules
At present, stationary phases based on ionic liquids are a promising and widely used technique in gas chromatography, yet they remain poorly studied.
Anastasia Yu. Sholokhova, Svetlana A. Borovikova   +1 more
doaj   +1 more source

Isocratic Resolution of Fluoroquinolone-Based Antibiotics on the Phenylethyl-Bonded Phase under Nonaqueous Elution: A Consideration of the Separation Mechanism

International Journal of Analytical Chemistry, 2018
This paper reports the isocratic resolution of 10 fluoroquinolone-based antibiotics and their precursors on the phenylethyl-bonded phase under the elution of the nonaqueous mobile phase composed of acetonitrile, methanol, acetic acid, and triethylamine ...
Yu-Xuan Gao, Shushi Chen
doaj   +1 more source

Reversed-phase fused-core HPLC modeling of peptides

Journal of Pharmaceutical Analysis, 2013
Different fused-core stationary phase chemistries (C18, Amide, Phenyl-hexyl and Peptide ES-C18) were used for the analysis of 21 structurally representative model peptides.
Matthias D'Hondt, Bert Gevaert, Sofie Stalmans, Sylvia Van Dorpe, Evelien Wynendaele, Kathelijne Peremans, Christian Burvenich, Bart De Spiegeleer   +7 more
doaj   +1 more source

Gas Chromatographic Retention Index Prediction Using Multimodal Machine Learning

IEEE Access, 2020
Gas chromatography is a widely used method in analytical chemistry and metabolomics. Using gas chromatography, vaporizable compounds can be separated for their further identification.
Dmitriy D. Matyushin, Aleksey K. Buryak
doaj   +1 more source

Investigation of retention behavior of imidazoline receptor ligands on mixedmode HILIC stationary phase [PDF]

, 2018
Retention mechanism in the hydrophilic interaction liquid chromatography (HILIC) mode is complex and still a subject of many controversial interpretations. In order to describe the HILIC retention mechanism, different retention models can be employed.
Popović-Nikolić, Marija, Popović, Gordana, Agbaba, Danica, Obradović, Darija, Oljačić, Slavica   +4 more
core   +3 more sources

Comparison of the Retention and Separation Selectivity of Aromatic Hydrocarbons with Polar Groups in RP-HPLC Systems with Different Stationary Phases and Eluents

Molecules, 2020
In this manuscript, the retention of aromatic hydrocarbons with polar groups has been compared for systems with various nonpolar columns of the types from C3 to C18 and different mobile phases composed of methanol, acetonitrile, or tetrahydrofuran as ...
Anna Klimek-Turek, Beata Misiołek, Tadeusz H. Dzido   +2 more
doaj   +1 more source