Results 21 to 30 of about 33,835 (260)

Peptide retention time prediction for immobilized artificial membrane phosphatidylcholine stationary phase: method development and preliminary observations

ADMET and DMPK, 2018
Development of the first peptide retention prediction model for immobilized artificial membrane phosphatidylcholine (IAM.PC) stationary phase is reported. 2D LC-MS/MS analysis of a whole cell lysate of S. cerevisiae yielded a retention dataset of ~29,500
Daniel Gussakovsky, Haley Neustaeter, Victor Spicer, Oleg Krokhine   +3 more
doaj   +1 more source

Fabrication of naphthol-based phenolic polymer coated-silica for mixed-mode chromatography

Journal of Chromatography Open, 2022
This paper introduces a novel phenolic resin-coated silica stationary phase grafted from the surface of amino-functionalized porous silica microspheres through copolymerization of 1,5-dihydroxynaphthalene and 1,3,5-trioxane in the dispersed state ...
Yongxing Hu, Hirotaka Ihara, Makoto Takafuji   +2 more
doaj   +1 more source

The thermodynamic study of morpholinium 2-((4-(2-methoxyphenyl)-5-(pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetate and its technological impurities in hydrophilic chromatography

Журнал органічної та фармацевтичної хімії, 2020
Aim. To study the dependence of the retention of morpholinium 2-((4-(2-methoxyphenyl)-5-(pyridinyl)-4H-1,2,4-triazol-3-yl)thio)acetate and its technological impurities on temperature, as well as determine the thermodynamic characteristics of the transfer
B. O. Varynskyi
doaj   +1 more source

Determination of thermodynamic parameters of morpholinium 2-(5-(pyridinyl)-1,2,4-triazole-3-ylthio)acetate and its impurities in conditions of reverse phase chromatography

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
The study of thermodynamic retention parameters helps to optimize the separation process in chromatography, and it is also possible to detrmine the nature of the interaction of analyts with the stationary phase.
B. O. Varynskyi
doaj   +1 more source

Isothermal retention indices on poly(3,3,3-trifluoropropylmethylsiloxane) stationary phases

Journal of Chromatography A, 2007
Isothermal retention indices (I) of 56 solutes of varied chemical nature and polarity were determined by a well-proven accurate method on poly(3,3,3-trifluoropropylmethylsiloxanes) with trifluoropropyl group percentages between 0 and 50% within the 353-413 K temperature range.
Lebrón-Aguilar, Rosa, Quintanilla-López, Jesús Eduardo, Tello, Ana María, Santiuste, José María   +3 more
openaire   +2 more sources

Comparison of Various Chromatographic Systems for Identification of Vortioxetine in Bulk Drug Substance, Human Serum, Saliva, and Urine Samples by HPLC-DAD and LC-QTOF-MS

Molecules, 2020
Background: Determination of psychotropic drugs in clinical study is significant, and the establishment of methodologies for these drugs in biological matrices is essential for patients’ safety.
Anna Petruczynik, Karol Wróblewski, Krzysztof Wojtanowski, Tomasz Mroczek, Dariusz Juchnowicz, Hanna Karakuła-Juchnowicz, Tomasz Tuzimski   +6 more
doaj   +1 more source

Development and Validation of Retention Models in Supercritical Fluid Chromatography for Impregnation Process Design

Applied Sciences, 2021
The retention factor is the key quantity for the thermodynamic analysis of the retention mechanism in chromatographic experiments. In this work, we measure retention factors for moderately polar solutes on four silica-based porous matrices as stationary ...
Miaotian Sun, Zeynep Ülker, Zhixing Chen, Sivaraman Deeptanshu, Monika Johannsen, Can Erkey, Pavel Gurikov   +6 more
doaj   +1 more source

Silica-Based Stationary Phase with Surface Bound N-Acetyl-glucosamine for Hydrophilic Interaction Liquid Chromatography

Molecules, 2023
A hydrophilic silica-based stationary phase with surface bound N-acetylglucosamine (GlcNAc-silica) was prepared in house and characterized physically via Fourier transform infrared (FTIR) analysis and thermogravimetric analysis (TGA) and ...
Vaithilingam Rajendiran, Ziad El Rassi
doaj   +1 more source

Prediction of Bleeding via Simulation of Hydrodynamics in Centrifugal Partition Chromatography

Separations
Centrifugal Partition Chromatography (CPC) utilizes a two-phase liquid–liquid system as mobile and stationary phases. During operation, the latter continuously drains out of the rotor, despite it being in fact stationary, leading to decreasing separation
Felix Buthmann, Sophia Volpert, Jörg Koop, Gerhard Schembecker   +3 more
doaj   +1 more source

In-Column Dehydration Benzyl Alcohols and Their Chromatographic Behavior on Pyridinium-Based Ionic Liquids as Gas Stationary Phases

Molecules
At present, stationary phases based on ionic liquids are a promising and widely used technique in gas chromatography, yet they remain poorly studied.
Anastasia Yu. Sholokhova, Svetlana A. Borovikova   +1 more
doaj   +1 more source