Results 71 to 80 of about 2,833 (266)

Internationalism versus Statism and Globalism

open access: yes, 2012
This chapter examines contemporary debates about statism and globalism. Statists need a necessary condition for justice to apply. They must tell us what it is about states that renders such principles applicable, and does so only in states. The quest for
Mathias Risse
core   +1 more source

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

open access: yesAdvanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy   +13 more
wiley   +1 more source

A non-ideal global basic structure

open access: yesEtikk i Praksis: Nordic Journal of Applied Ethics, 2016
Focusing on the basic structure as the subject of justice has tended to lead theorists to make a choice: either there is no global basic structure and therefore obligations of justice remain domestic only (the statist position) or there is sufficient ...
Sabrina Martin
doaj   +1 more source

Force–Displacement Characterization of PNIPAM Microactuators

open access: yesAdvanced Robotics Research, EarlyView.
A method to experimentally establish a force–displacement diagram of poly(N‐isopropyl acrylamide) (PNIPAM) microactuators, printed by 2PP, is presented herein. PNIPAM is a hydrogel whose volume and stiffness change with temperature due to the absorption or release of water.
Manon Cassignol   +4 more
wiley   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

open access: yesAdvanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin   +20 more
wiley   +1 more source

A strict statism for motivating reasons

open access: yes
Practical motivating reasons are the reasons in light of which an agent acts. This paper aims to defend the thesis that practical motivating reasons are obtaining states of affairs. This conception can be called strict statism.
Molina, Yohan
core   +1 more source

Phosphorylated STYK1 Promotes Gemcitabine Resistance via Autophagy‐Mediated Cancer Stemness in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Gemcitabine resistance remains a major challenge in pancreatic ductal adenocarcinoma. This study identifies STYK1 as a key mediator of chemoresistance through autophagy‐dependent maintenance of cancer stemness. Gemcitabine‐activated AMPK phosphorylates STYK1 at Ser91 and Ser304, enhancing autophagy and stemness.
Xueying Dong   +20 more
wiley   +1 more source

Global justice and resource curse combining statism and cosmopolitanism

open access: yes, 2022
"This book explores whether any theory alone is sufficiently capable of resolving the complexity of global justice, arguing that a combination of statism and cosmopolitanism is needed. In current times, xenophobia, nationalism and populism have amplified
Abumere, Frank Aragbonfoh
core  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Análisis de la regulación primaria de la frecuencia con motores fuel oil y centrales termoeléctricas; Primary frequency regulation analysis with Fuel Oil Engines and steam turbine

open access: yesRevista Científica de Ingeniería Energética, 2011
En este artículo se mencionan los conceptos básicos del proceso de regulación de frecuencia, así comosu importancia para una correcta operación del sistema eléctrico.
Ivett Martín González   +1 more
doaj  

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