Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Statistical Policy Working Paper 9. Contracting for Surveys
Surveys are a major source of data for many agencies of the Federal Government. However, beyond the general standards there is no specific guidance on the use by Federal agencies of contractors for the conduct of surveys.
United States. Federal Committee on Statistical Methodology
core +1 more source
Background: An effective healthcare system relies on sufficient and competent human resources. However, many countries face staff shortages, burnout, and turnover, which threaten the quality and safety of care.
Olga Cerela-Boltunova +2 more
doaj +1 more source
Localization of the Knowledge Workers’ Productivity Questionnaire and Evaluation of the Productivity of Knowledge Workers of the Central Field of Shiraz University of Medical Sciences [PDF]
Introduction: Human resources impose a vast expense on health organizations. Therefore, improvement of the productivity of human resources is of considerable concern to executive managers of every country.
Nahid Hatam +5 more
doaj
Characteristics and patterns of rare malignancies published in Rare Tumors
Rare Tumors is an international peerreviewed medical journal established in 2009. The journal is focused on rare cancers and aims to expand upon current knowledge on their presentation, diagnosis, management, and outcomes.
Jacob Habboush +6 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The subcommittee reviewed training and development at its six member agencies \u2014 Bureau of the Census, Bureau of Labor Statistics, Centers for Disease Control and Prevention, Energy Information Administration, National Agricultural Statistics Service,
United States. Federal Committee on Statistical Methodology. Subcommittee on Survey and Statistical Training
core +1 more source
Tutorial on Bonferroni Correction as a Post Hoc Analysis of a Significant Chi-Squared Test: A Methodological Guide in Food Science [PDF]
Background: In medical research, analyzing the relationship between two categorical variables is common. While chi-square tests (e.g., Pearson's, McNemar's, and Cochran-Mantel-Haenszel) can determine if a significant association exists, they do not ...
F. Madadizadeh, M. Abdoli
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

