Results 161 to 170 of about 8,739,134 (290)

Statistical Reporting Quality in Physical Medicine and Rehabilitation Journals: A Comparative Analysis of SCI-E and TR Indexed Publications. [PDF]

Eurasian J Med
Şahbaz T, Özen Yorgancıgil G, Dirican A.   +2 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Effect of Quality Control Circle Activities on Reducing the Failure Rate of Surgical Instrument Pre-Treatment

Risk Management and Healthcare Policy
Yandan Wang,1 Xiulan Zhou,2 Yanqiu Zhu,1 Yuanmei Dan,1 Zeping Huang,1 Ling Xiang1 1Department of Sterile Processing Nursing, Sichuan Friendship Hospital, Chengdu, Sichuan, People’s Republic of China; 2Department of Nursing, Sichuan Friendship Hospital ...
Wang Y, Zhou X, Zhu Y, Dan Y, Huang Z, Xiang L   +5 more
doaj  

Effects of Statistical Learning on Target Detection Speed Can Reflect Prediction. [PDF]

Cogn Sci
Batterink LJ, Herrera-Chaves D, Köhler S.   +2 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Big data research: the importance of the data-generating process and domain expertise. [PDF]

World Psychiatry
Smoller JW.
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The effect of manuscript characteristics on quality assessment of scientific manuscripts in psychology. [PDF]

PLoS One
Augusteijn HEM, Wicherts JM, Sijtsma K, van Assen MALM.   +3 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Coupling between statistical learning and interference suppression. [PDF]

Psychol Res
Horváth K, Nemeth D, Janacsek K, Kóbor A.   +3 more
europepmc   +1 more source