Results 241 to 250 of about 8,739,134 (290)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Fibronectin mediates APOE4-driven blood-brain barrier dysfunction in Alzheimer's disease. [PDF]

Nat Aging
Bhattarai P, Yilmaz E, Cakir EÖ, Tayran H, Haq I, Murphy D, Keller JN, Le Grand Q, Eschbach JO, Celikkaya H, Cosacak MI, Yüceer Korkmaz H, Lee AJ, Haage V, Ma Y, Wang X, Nelson N, Lin W, Zhang Y, Turgutalp B, de Leeuw SM, Patel R, Jülich D, İş Ö, Holley SA, De Jager PL, Freudenberg U, Werner C, St George-Hyslop P, Ertekin-Taner N, Debette S, Elahi FM, Fisher ES, Phatnani H, Teich AF, Tubbesing K, Bertucci T, Temple S, Nuriel T, Vardarajan BN, Mayeux R, Kizil C.   +41 more
europepmc   +1 more source

Prediction of the properties of sintered copper-graphite composites using response surface methodology. [PDF]

PLoS One
Ankit, Kumar V, Singh MK, Ji G, Kutar SP, Gupta SK, Singh RB, Gautam RKS, Katiyar JK.   +8 more
europepmc   +1 more source

CCL7-CCR3 signaling mediates olfactory dysfunction in a mouse model of allergic rhinitis. [PDF]

Front Immunol
Yang T, Shen H, Zhao T, Mou Y, Hu Y, Song X, Wang Y, Chen Y, Wang H, Ren C, Song X.   +10 more
europepmc   +1 more source

Data Compression of the D1200 Suite: Achieving the Optimal Balance Between Size and Accuracy with the Diet-D200 Subset. [PDF]

J Comput Chem
Soriano-Agueda L.
europepmc   +1 more source

Interpreting Heterogeneity Beyond I² in Meta-Analysis: Integrating Statistical Metrics With Clinical Judgement. [PDF]

J Eval Clin Pract
Ferreira MHL, Câmara LC, Ferreira FDV, Melo MS, de Souza RF, de Aguiar DR, Pereira SIDS, Junior NC.   +7 more
europepmc   +1 more source

Proceedings of the Dublin Statistical Society: Eleventh Session, First Meeting -

Dublin Statistical Society
core  

Proceedings of the Dublin Statistical Society: Eleventh Session, Fourth Meeting -

Dublin Statistical Society
core  

Proceedings of the Dublin Statistical Society: Fifteenth Session, First Meeting -

Dublin Statistical Society
core