Results 21 to 30 of about 16,414,782 (185)

Justice Data Base Directory [PDF]

open access: yes, 1992
The Justice Data Base Directory was originally published in 1988 with an introduction, 8 chapters describing Alaska justice agencies and their data holdings, and an index. It was published in looseleaf notebook format for easy updating. Four updates were
Alaska Justice Statistical Analysis Unit   +1 more
core  

Statistical ensembles without typicality [PDF]

open access: yes, 2006
Maximum-entropy ensembles are key primitives in statistical mechanics from which thermodynamic properties can be derived. Over the decades, several approaches have been put forward in order to justify from minimal assumptions the use of these ensembles ...
Boes, Paul   +3 more
core   +5 more sources

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

Statistical models for market segmentation [PDF]

open access: yes, 2004
It is an essential element of market research that customer preferences are considered and the heterogeneity of these preferences is recognized. By segmenting the market into homogeneous clusters the preferences of customers is addressed.
Camilleri, Liberato   +2 more
core  

Boosted Statistical Mechanics

open access: yes, 2015
Based on the fundamental principles of Relativistic Quantum Mechanics, we give a rigorous, but completely elementary, proof of the relation between fundamental observables of a statistical system when measured relatively to two inertial reference frames,
Testa, Massimo
core   +1 more source

Towards a Statistical Geometrodynamics [PDF]

open access: yes, 2003
Can the spatial distance between two identical particles be explained in terms of the extent that one can be distinguished from the other? Is the geometry of space a macroscopic manifestation of an underlying microscopic statistical structure?
Caticha, Ariel
core   +3 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Statistical approach to optimization of the transesterification reaction from sorrel (hibiscus sabdariffa) oil [PDF]

open access: yes, 2012
In an effort to optimize the reaction conditions of biodiesel production from Sorrel seed oil, Response Surface Methodology (RSM) was applied and the effects of reaction temperature, catalyst amount, reaction time and methanol/oil molar ratio, and ...
Adepoju, Tunde .F.   +3 more
core  

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

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