Results 301 to 310 of about 17,333,893 (364)

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

open access: yesFEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno   +12 more
wiley   +1 more source

Best practices and tools in R and Python for statistical processing and visualization of lipidomics and metabolomics data. [PDF]

open access: yesNat Commun
Idkowiak J   +19 more
europepmc   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu   +12 more
wiley   +1 more source

Atypical contribution of caspase-3 to melanoma cancer cell motility by regulation of coronin 1B activity. [PDF]

open access: yesCell Death Dis
Berthenet K   +14 more
europepmc   +1 more source

Reproducibility Crossroads: Impact of Statistical Choices on Proteomics Functional Enrichment. [PDF]

open access: yesInt J Mol Sci
Biełło KA   +5 more
europepmc   +1 more source

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