Results 71 to 80 of about 17,069,027 (366)

TYPES OF TOOTH DISCOLORATION IN ADULTS OF RAMADI CITY, AL-ANBAR PROVINCE, IRAQ: STATISTICAL STUDY [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2012
: During the period June 2005 to June 2006, 158 patients with teeth discoloration were interviewed regarding the causes of discoloration. Most common cause of discoloration teeth in females was the caries, whereas trauma and dentin development problems ...
Hamid Hammad Anizy
doaj   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

Statistical properties and statistical interaction for particles with spin: Hubbard model in one dimension and statistical spin liquid

, 1994
We derive the statistical distribution functions for the Hubbard chain with infinite Coulomb repulsion among particles and for the statistical spin liquid with an arbitrary magnitude of the local interaction in momentum space.
D.V. Khveshchenko, E.H. Lieb, F.D.M. Haldane, J. Carmelo, J. Carmelo, J. Hubbard, J. Spałek, J. Spałek, J. Spałek, J. Spałek, J. Spałek, J. Spałek, J.B. Sokoloff, J.M. Leinaas, Jozef Spal/ek, K. Byczuk, Krzysztof Byczuk, M. Ogata, M.V.N. Murthy, N. Andrei, P.M. Chaikin, P.W. Anderson, P.W. Anderson, Y. Hatsugai   +23 more
core   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

Statistical Properties of Strings [PDF]

, 1994
We investigate numerically the configurational statistics of strings. The algorithm models an ensemble of global $U(1)$ cosmic strings, or equivalently vortices in superfluid $^4$He.
Allega, Austin, Bowick, Bowick, Chuang, Chuang, Cohen, Copeland, Copeland, Cormen, de Gennes, Domb, Edwards, Hagedorn, Hendry, Hindmarsh, K. Strobl, Kibble, Kibble, Kibble, Kibble, Leese, M. Hindmarsh, Mitchell, Mondello, Onsager, Rivier, Rudaz, Sakellariadou, Scherrer, Smith, Sokal, Stauffer, Sundborg, Vachaspati, Vachaspati, Vilenkin   +36 more
core   +2 more sources

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Factors influencing adherence to psychopharmacological medications in psychiatric patients: a structural equation modeling approach

Patient Preference and Adherence, 2017
Carlos De las Cuevas,1 Jose de Leon,2–4 Wenceslao Peñate,5 Moisés Betancort5 1Departamento de Medicina Interna, Dermatología y Psiquiatría, Universidad de La Laguna, Canary Islands, Spain; 2Mental Health Research Center
De las Cuevas C, de Leon J, Peñate W, Betancort M   +3 more
doaj  

Quantum Statistical Manifolds

, 2018
Quantum information geometry studies families of quantum states by means of differential geometry. A new approach is followed with the intention to facilitate the introduction of a more general theory in subsequent work.
Naudts, Jan
core   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source