Results 91 to 100 of about 11,468,989 (327)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Statistical topological data analysis using persistence landscapes [PDF]

open access: yes, 2015
We define a new topological summary for data that we call the persistence landscape. Since this summary lies in a vector space, it is easy to combine with tools from statistics and machine learning, in contrast to the standard topological summaries ...
Bubenik, Peter
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Evolution of a geometric constant along the Ricci flow

open access: yesJournal of Inequalities and Applications, 2016
In this paper, we establish the first variation formula of the lowest constant λ a b ( g ) $\lambda_{a}^{b}(g)$ along the Ricci flow and the normalized Ricci flow, such that to the following nonlinear equation there exist positive solutions: − Δ u + a u ...
Guangyue Huang, Zhi Li
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Development of New Predictive Equations for the Resting Metabolic Rate (RMR) of Women with Lipedema

open access: yesMetabolites
This study aimed to develop a novel predictive equation for calculating resting metabolic rate (RMR) in women with lipedema. We recruited 119 women diagnosed with lipedema from the Angiology Outpatient Clinic at Wroclaw Medical University, Poland.
Małgorzata Jeziorek   +4 more
doaj   +1 more source

Radial Symmetry and Monotonicity of Solutions to a System Involving Fractional p-Laplacian in a Ball

open access: yesAdvances in Mathematical Physics, 2018
In this paper, we study a nonlinear system involving the fractional p-Laplacian in a unit ball and establish the radial symmetry and monotonicity of its positive solutions. By using the direct method of moving planes, we prove the following result.
Linfen Cao, Xiaoshan Wang, Zhaohui Dai
doaj   +1 more source

A Statistical Approach in the Analysis of Geometrical Product Specification during the Cold Tube Drawing Process [PDF]

open access: gold, 2022
Ladislav Morovič   +5 more
openalex   +1 more source

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