Results 101 to 110 of about 11,657,504 (319)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

An Algorithm for Creating a Synaptic Cleft Digital Phantom Suitable for Further Numerical Modeling

Algorithms
One of the most significant applications of mathematical numerical methods in biology is the theoretical description of the convectional reaction–diffusion of chemical compounds.
Olga A. Zagubnaya, Yaroslav R. Nartsissov   +1 more
doaj   +1 more source

Some bounds for the Z-eigenpair of nonnegative tensors

Journal of Inequalities and Applications, 2019
Tensor eigenvalue problem is one of important research topics in tensor theory. In this manuscript, we consider the properties of Z-eigenpair of irreducible nonnegative tensors. By estimating the ratio of the smallest and largest components of a positive
Xiaoyu Ma, Yisheng Song
doaj   +1 more source

Statistical methods of SNP data analysis with applications [PDF]

, 2011
Various statistical methods important for genetic analysis are considered and developed. Namely, we concentrate on the multifactor dimensionality reduction, logic regression, random forests and stochastic gradient boosting.
Bulinski, Alexander, Butkovsky, Oleg, Shashkin, Alexey, Yaskov, Pavel   +3 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Statistical analysis of the impact of environmental temperature on the exponential growth rate of cases infected by COVID-19

, 2020
G. Livadiotis
openalex   +2 more sources

Analysis of students difficulties in mathematical abstraction thinking in the mathematics statistic course

, 2021
Arfatin Nurrahmah, Zaenuri Zaenuri, Wardono   +2 more
openalex   +1 more source

A statistical analysis of lexis in conversational english [PDF]

, 1990
Chapter ElevenZadanie pt. „Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki” nr 885/P-DUN/2014 zostało dofinansowane ze środków MNiSW w ramach działalności ...
Lewandowska-Tomaszczyk, Barbara
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Excess life-years and productive life-years lost in Poland through the COVID-19 pandemic and post-pandemic years

Archives of Public Health
Background Poland’s COVID-19 experience resulted in one of Europe’s most severe mortality shocks, yet the share of lost life-years occurring at working age has not been quantified.
Błażej Łyszczarz, Jakub Wojtasik, Tomasz Zieliński   +2 more
doaj   +1 more source