Results 71 to 80 of about 11,468,989 (327)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Statistical Analysis for Tidal Flat Classification and Topography Using Multitemporal SAR Backscattering Coefficients [PDF]
, 2021 Keunyong Kim +3 more
openalex +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Multiscale statistical analysis of coronal solar activity
, 2016 Multi-filter images from the solar corona are used to obtain temperature maps which are analyzed using techniques based on proper orthogonal decomposition (POD) in order to extract dynamical and structural information at various scales.
del-Castillo-Negrete, Diego +2 more
core +2 more sources
A Statistical Analysis of Magnetic Field Changes in the Photosphere during Solar Flares Using High-cadence Vector Magnetograms and Their Association with Flare Ribbons [PDF]
, 2023 Rahul Yadav, Maria D. Kazachenko
openalex +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
AxiomsThis paper establishes two novel recurrence relations for Stirling numbers of the second kind—an L recurrence and a vertical recurrence—discovered through a probabilistic analysis of Poisson higher-order origin moments.
Ying-Ying Zhang, Dong-Dong Pan
doaj +1 more source
The Statistical Analysis of Behavioural Latency Measures [PDF]
, 1997 This article concerns two important problems with the statistical analysis of behavioural latency measures: they typically have severely skewed distributions, and are often censored (truncated).
Budaev, Dr. Sergey
core
Statistical Analysis of Airport Network of China
, 2003 Through the study of airport network of China (ANC), composed of 128 airports (nodes) and 1165 flights (edges), we show the topological structure of ANC conveys two characteristics of small worlds, a short average path length (2.067) and a high degree of
A.-L. Barabási +11 more
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source