Results 71 to 80 of about 11,222,791 (325)
Pair-Copula Constructions for Financial Applications: A Review
Econometrics, 2016 This survey reviews the large and growing literature on the use of pair-copula constructions (PCCs) in financial applications. Using a PCC, multivariate data that exhibit complex patterns of dependence can be modeled using bivariate copulae as simple ...
Kjersti Aas
doaj +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Statistical topological data analysis using persistence landscapes [PDF]
, 2015 We define a new topological summary for data that we call the persistence landscape. Since this summary lies in a vector space, it is easy to combine with tools from statistics and machine learning, in contrast to the standard topological summaries ...
Bubenik, Peter
core
Business Cycles: A Theoretical, Historical, and Statistical Analysis of the Capitalist Process [PDF]
, 1940 Ervin K. Zingler, Joseph A. Schumpeter
openalex +2 more sources
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Statistical Analysis of High-Flow Traffic States
, 2013 The relation between the fundamental observables of traffic flow (i.e., vehicle density, flow rate, and average velocity) is of great importance for the study of traffic phenomena. Probably the most common source of such data are inductive loop detectors,
Brügmann, Johannes +3 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Protein sectors: statistical coupling analysis versus conservation
, 2014 Statistical coupling analysis (SCA) is a method for analyzing multiple sequence alignments that was used to identify groups of coevolving residues termed "sectors".
Colwell, Lucy J. +2 more
core +4 more sources
Variational Bayesian Variable Selection for High-Dimensional Hidden Markov Models
MathematicsThe Hidden Markov Model (HMM) is a crucial probabilistic modeling technique for sequence data processing and statistical learning that has been extensively utilized in various engineering applications.
Yao Zhai +3 more
doaj +1 more source