Results 91 to 100 of about 501,153 (319)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Identifying the best FDA-endorsed healthy label designs through best-worst scaling experiment

Public Health Nutrition
Objective: This study aims to assess consumer preferences for fifteen proposed front-of-package ‘Healthy’ label candidates under the Food and Drug Administration’s (FDA) of the US updated guidelines for the ‘Healthy’ label.
Jianhui Liu, Bachir Kassas, John Lai, Rodolfo M. Nayga   +3 more
doaj   +1 more source

Inference with interference between units in an fMRI experiment of motor inhibition

, 2017
An experimental unit is an opportunity to randomly apply or withhold a treatment. There is interference between units if the application of the treatment to one unit may also affect other units.
Aron A. R., Chiang-Shan R. Li, Cochran W. G., Conover W. J., Cox D. R., David O., Deshpande J. V., Duann J. R., Dylan S. Small, Fisher R. A., Forstmann B. U., Friston K. J., Friston K. J., Hoeffding W., Hudgens M. G., Lehmann E. L., Lehmann E. L., Li C. S., Lindquist M. A., Lindquist M. A., Lindquist M. A., Neyman J., Neyman J., Neyman J., Orban J., Paul R. Rosenbaum, Puri M. L., Rosenbaum P. R., Rosenbaum P. R., Rosenbaum P. R., Rosenbaum P. R., Rosenbaum P. R., Rubin D. B., Salsburg D. S., Simmonds D. J., Sobel M. E., Stephenson W. R., Stephenson W. R., Tukey J. W., Weiss L., Welch B. L., Xi Luo   +41 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

An analytical review of statistical methods and designs in agricultural science Una revisión analítica de diseños y métodos estadísticos en ciencias agrícolas

Agronomía Colombiana, 1994
Scientilic papers of six wellknown international journal of agricultural research (Agronomy Journal, Crop Science, Plant Physiology, Phytopathology, Plant Disease, Journal of Economic Entomology) and the Revista ICA of Colombia, were revised taking the ...
Martínez W. Orlando, Galindo Ricardo
doaj  

There Once Was a 9-Block …- A Middle-School Design for Probability and Statistics

Journal of Statistics Education, 2006
ProbLab is a probability-and-statistics unit developed at the Center for Connected Learning and Computer-Based Modeling, Northwestern University.
Dor Abrahamson, Ruth M. Janusz, Uri Wilensky   +2 more
openaire   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

A general theory of minimum aberration and its applications

, 2005
Minimum aberration is an increasingly popular criterion for comparing and assessing fractional factorial designs, and few would question its importance and usefulness nowadays.
Cheng, Ching-Shui, Tang, Boxin
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

On the understanding of zinc-oxide eugenol cement use prior to etch-rinse bonding strategies

Indian Journal of Dental Research, 2019
Context: Zinc-oxide eugenol (ZOE) is frequently used due to its satisfactory biological response, sedative effect on the pulp, and easy removal. However, literature is very controversial about the influence of the temporary cement-containing eugenol on ...
Catarina Pires Bezerra, Cristiano Fukugawa Campos, Julio Leite, Marina Struncová Fernandes, Cintia Helena Coury Saraceni, Flávia Pires Rodrigues, Maristela Dutra-Correa   +6 more
doaj   +1 more source