Results 11 to 20 of about 5,575,505 (199)

Modelling longitudinal binary outcomes with outcome dependent observation times: an application to a malaria cohort study

open access: yesMalaria Journal, 2022
Background  In spite of the global reduction of 21% in malaria incidence between 2010 and 2015, the disease still threatens many lives of children and pregnant mothers in African countries.
Adelino Martins   +5 more
doaj   +1 more source

Maintaining Precision in Survey Estimates while Adjusting for Conditional Bias at the Subnational Level through Calibration Weighting

open access: yesSurvey Research Methods, 2017
Calibration weighting improves inference by adjusting for observed differences between the realized sample and the population. Unfortunately, a commonly-used linearization-based variance estimator often does not account for the increased efficiency ...
Bonnie E Shook-Sa   +7 more
doaj   +1 more source

Robust Estimation for Semi-Functional Linear Model with Autoregressive Errors

open access: yesMathematics, 2023
It is well-known that the traditional functional regression model is mainly based on the least square or likelihood method. These methods usually rely on some strong assumptions, such as error independence and normality, that are not always satisfied ...
Bin Yang   +3 more
doaj   +1 more source

Confidence Intervals for Assessing Non-Inferiority with Assay Sensitivity in a Three-Arm Trial with Normally Distributed Endpoints

open access: yesMathematics, 2022
Various approaches including hypothesis test and confidence interval (CI) construction have been proposed to assess non-inferiority and assay sensitivity via a known fraction or pre-specified margin in three-arm trials with continuous or discrete ...
Niansheng Tang, Fan Liang
doaj   +1 more source

Variational Bayesian Inference in High-Dimensional Linear Mixed Models

open access: yesMathematics, 2022
In high-dimensional regression models, the Bayesian lasso with the Gaussian spike and slab priors is widely adopted to select variables and estimate unknown parameters. However, it involves large matrix computations in a standard Gibbs sampler.
Jieyi Yi, Niansheng Tang
doaj   +1 more source

A nonparametric Bayesian continual reassessment method in single-agent dose-finding studies

open access: yesBMC Medical Research Methodology, 2018
Background The main purpose of dose-finding studies in Phase I trial is to estimate maximum tolerated dose (MTD), which is the maximum test dose that can be assigned with an acceptable level of toxicity.
Niansheng Tang, Songjian Wang, Gen Ye
doaj   +1 more source

Why estimands are needed to define treatment effects in clinical trials

open access: yesBMC Medicine, 2023
Background The estimand for a clinical trial is a precise definition of the treatment effect to be estimated. Traditionally, estimates of treatment effects are based on either an ITT analysis or a per-protocol analysis.
Oliver N. Keene   +4 more
doaj   +1 more source

Assessing COVID-19 vaccine hesitancy and barriers to uptake in Sub-Saharan Africa

open access: yesCommunications Medicine, 2023
Background Despite improved availability of COVID-19 vaccines in Sub-Saharan Africa, vaccination campaigns in the region have struggled to pick up pace and trail the rest of the world.
Philip Wollburg   +3 more
doaj   +1 more source

Spatial Regression in the Presence of a Hierarchical Transportation Network: Application to Land Price Analysis

open access: yesFrontiers in Sustainable Cities, 2022
Transportation networks have a hierarchical structure, and the spatial scale of their impact on urban growth differs depending on the hierarchy. However, in empirical analyses of the impacts that transportation has on land use and prices, such hierarchy ...
Daisuke Murakami, Hajime Seya
doaj   +1 more source

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks   +5 more
wiley   +1 more source

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