Results 151 to 160 of about 3,514,467 (321)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Scenario-based mechanistic interpretation of multivariate statistical evidence to assess the aquifer-scale competition for electron donors using sparse and incomplete hydrogeochemical data [PDF]

Diego Di Curzio, Sergio Rusi, Boris van Breukelen   +2 more
openalex   +1 more source

Interpretation of groundwater chemistry data using multivariate statistical techniques [PDF]

, 2016
R Dehghanzadeh, N Hir, J Sis, H Taghipour, K Dragon, A Elfeki, H Ewea, N Al-Amri, H Ewea, M Forrest, J Kulongoski, M Edwards, C Farrar, K Belitz, R Norris, C Griebler, H Stein, C Kellermann, S Berkhoff, H Brielmann, S Schmidt, D Selesi, C Steube, A Fuchs, H Hahn, H Hahn, A Fuchs, A Ibekwe, M Leddy, R Bold, A Graves, M Jabal, I Abustan, M Rozaimy, El Najar, H, C Lin, M Abdullah, S Praveena, A Yahaya, B Musta, M Morsi, A Farrag, A Elewa, El Sayed, E, A Ramette, F Rehman, H Abuelnaga, H Harbi, C Tariq, A Atef, F Rehman, T Cheema, F Rehman, S Helmy, M Hussein, H Ali, S Schmidt, J Hellweg, H Hahn, T Hatton, W Humphreys, M Sharaf, K Srinivasamoorthy, M Gopinath, S Chidambaram, M Vasanthavigar, V Sarma, A Subyani, Al Ahmadi, M, L Sun, H Gui, M Suresh, B Gurugnanam, S Vasudevan, B Rajeshkanna, K Dharanirajan, N Prabhakaran, A Nagar, L Zhang, X Song, J Xia, R Yuan, Y Zhang, X Liu, D Han   +87 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

INTERPRETATION OF STATISTICAL DATA: THE IMPORTANCE OF AFFECTIVE EXPRESSIONS

, 2017
Tamires Nogueira Queiroz, Carlos Eduardo Ferreira Monteiro, Liliane Maria Teixeira Lima de Carvalho, Karen François   +3 more
openalex   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Statistical Transformation and the Interpretation of Inpatient Glucose Control Data From the Intensive Care Unit [PDF]

, 2014
George E. Saulnier, Janna C. Castro, Curtiss B. Cook   +2 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Network meta-analyses in IBD: pitfalls and promise for clinicians. [PDF]

Therap Adv Gastroenterol
Gordon M.
europepmc   +1 more source