Results 11 to 20 of about 4,175 (169)

Common pitfalls in statistical analysis: The perils of multiple testing

Perspectives in Clinical Research, 2016
Multiple testing refers to situations where a dataset is subjected to statistical testing multiple times - either at multiple time-points or through multiple subgroups or for multiple end-points. This amplifies the probability of a false-positive finding.
Priya Ranganathan, C S Pramesh, Marc Buyse   +2 more
doaj   +1 more source

Atypical Teratoid Rhabdoid Tumor: Two Case Reports and an Analysis of Adult Cases with Implications for Pathophysiology and Treatment

Frontiers in Neurology, 2017
We present the first quantitative analysis of atypical teratoid rhabdoid tumors (ATRT) in adults, including two patients from our own institutions. These are of interest as one occurred during pregnancy and one is a long-term survivor.
Christopher Dardis, Jared Yeo, Kelly Milton, Lynn S. Ashby, Kris A. Smith, Shwetal Mehta, Emad Youssef, Jenny Eschbacher, Kathy Tucker, Laughlin Dawes, Neil Lambie, Elizabeth Algar, Elizabeth Hovey, Elizabeth Hovey   +13 more
doaj   +1 more source

Is the Bland-Altman plot method useful without inferences for accuracy, precision, and agreement? [PDF]

Revista de Saúde Pública
OBJECTIVE This study aims to propose a comprehensive alternative to the Bland-Altman plot method, addressing its limitations and providing a statistical framework for evaluating the equivalences of measurement techniques.
Paulo Sergio Panse Silveira, Joaquim Edson Vieira, José de Oliveira Siqueira   +2 more
doaj   +1 more source

On direct sequential analysis of heart rate variability signals [PDF]

Archive of Oncology, 2005
Heart rate variability analysis represents one of the most promising and the most commonly used quantitative measures of the cardiovascular autonomic regulatory system.
Bajić Dragana, Lončar-Turukalo Tatjana, Šibarević Olijandra   +2 more
doaj   +1 more source

Risk factors for recurrent vulvovaginal candidiasis [PDF]

Vojnosanitetski Pregled, 2010
Background/Aim. Recurrent vulvovaginal candidiasis is relatively frequent condition, and may have serious health consequences, like chronic vulvovaginal pain syndrome. The aim of our study was to determine possible risk factors for recurrent vulvovaginal
Janković Slobodan, Bojović Dragica, Vukadinović Dubravka, Daglar Elmedina, Janković Marija, Laudanović Dragomir, Lukić Vladan, Mišković Vesna, Potpara Zorica, Projović Ivana, Čokanović Vesna, Petrović Nadežda, Folić Marko, Savić Viktorija   +13 more
doaj   +1 more source

Randomized trial of dentists’ understanding: treatment benefit in absolute numbers vs relative risk reduction [PDF]

Brazilian Oral Research
This study aimed to assess whether dentists correctly understand the benefit of a dental treatment when it is presented using absolute numbers or relative risk reduction (RRR).
Paulo NADANOVSKY, Branca Heloisa de OLIVEIRA, Ronaldo LIRA-JUNIOR, Ana Paula Pires dos SANTOS   +3 more
doaj   +1 more source

Evaluation of agreement and correlation of three occlusal indices in an assessment of orthodontic treatment need [PDF]

Vojnosanitetski Pregled, 2011
Background/Aim. Occlusal indices are quantitative diagnostic indicators of malocclusion severity, orthodontic treatment need, complexity and outcome.
Đorđević Jelena, Šćepan Ivana, Glišić Branislav   +2 more
doaj   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source