Results 61 to 70 of about 353,990 (265)

A New Generalization of the Lomax Distribution with Increasing, Decreasing, and Constant Failure Rate

Modelling and Simulation in Engineering, 2017
Developing new compound distributions which are more flexible than the existing distributions have become the new trend in distribution theory. In this present study, the Lomax distribution was extended using the Gompertz family of distribution, its ...
Pelumi E. Oguntunde, Mundher A. Khaleel, Mohammed T. Ahmed, Adebowale O. Adejumo, Oluwole A. Odetunmibi   +4 more
doaj   +1 more source

Experimental Test of the “Special State” Theory of Quantum Measurement

Entropy, 2012
An experimental test of the “special state” theory of quantum measurement is proposed. It should be feasible with present-day laboratory equipment and involves a slightly elaborated Stern–Gerlach setup.
Lawrence S. Schulman
doaj   +1 more source

Dilemma of t-tests: Retaining or discarding choice and solutions [PDF]

Computational Ecology and Software, 2022
The t-test theory has laid the foundation of modern statistics and it is one of the main contents of statistics. This theory can be found in all statistics textbooks and is at the core of almost all applied statistics courses.
WenJun Zhang
doaj  

Statistical theory of deformation distributions in nuclear spectra

Physical Review C, 2018
The dependence of the nuclear level density on intrinsic deformation is an important input to dynamical nuclear processes such as fission. Auxiliary-field Monte Carlo (AFMC) method is a powerful method for computing nuclear level densities. However, the statistical distribution of intrinsic shapes is not readily accessible due to the formulation of ...
Mustonen, M. T., Gilbreth, C. N., Alhassid, Y., Bertsch, G. F.   +3 more
openaire   +3 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

On Approaching Normality Through Rectangular Distribution: Industrial Applications to Monitor Electron Gun and File Server Processes

Journal of Statistical Theory and Applications (JSTA)
Normal probability distribution is central to most statistical methods and their applications. In many real scenarios, the normality of the underlying phenomenon is not obvious.
Muhammad Riaz, Anwar H. Joarder, M. Hafidz Omar, Tahir Mahmood, Nasir Abbas   +4 more
doaj   +1 more source

New Advances in Distribution Theory and Its Applications

Mathematics
In recent years, the prolific development of new statistical distributions via various techniques has often led to increased complexity without necessarily enhancing model flexibility or parameter interpretability, a trend that has sometimes diminished ...
Filippo Domma, Francesca Condino
doaj   +1 more source