Results 71 to 80 of about 28,611,700 (297)

Unravelling historical cost developments of offshore wind energy in Europe [PDF]

open access: yes, 2016
This paper aims to provide insights in the cost developments of offshore wind energy in Europe. This is done by analysing 46 operational offshore wind farms commissioned after 2000.
van Sark, W. G J H M   +4 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Corrected Statistical Energy Analysis Model for Car Interior Noise

open access: yesAdvances in Mechanical Engineering, 2015
Statistical energy analysis (SEA) is a well-known method to analyze the flow of acoustic and vibration energy in a complex structure. For an acoustic space where significant absorptive materials are present, direct field component from the sound source ...
A. Putra, Al Munawir, W. M. Farid
doaj   +1 more source

Virginia Tech's Laboratory for Interdisciplinary Statistical Analysis Annual Report 2015-16

open access: yes, 2016
This annual report summarizes the activities of LISA, Virginia Tech’s Laboratory for Interdisciplinary Statistical Analysis, during the fall and spring semesters of the 2015-16 academic year.
Vance, Eric A., Pruitt, Tonya
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Analysis of Long-Term Performance of PV Systems [PDF]

open access: yes, 2015
This report describes the activities, conclusions and continued efforts undertaken in Subtask 1 by the participating countries in IEA-PVPS Task 13. Subtask 1 examines the PV power plant as a system.
Energy System Analysis   +5 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Identification of Statistical Energy Analysis Parameters from Measured Data

open access: yes, 2003
An approach for identifying statistical energy analysis (SEA) parameters from experimental investigation is presented. Specifically, a power flow realization method (PRM) and statistical energy analysis model improvement (SMI) technique using transient ...
Gregory, Joseph William
core  

CCS Infrastructure Development Scenarios for the Integrated Iberian Peninsula and Morocco Energy System [PDF]

open access: yes, 2013
This paper briefly illustrates a method to represent national energy systems and the geographical details of CCS infrastructures in the same technical-economic model. In the MARKAL-TIMES modeling framework a model of Morocco, Portugal and Spain with both
van den Broek, M.A.   +5 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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